[1]兰云竹综述,付莉*,毛熙光审校.影响精子DNA完整性高危因素及检测技术进展[J].中国计划生育和妇产科,2017,(1):29-32.
 LAN Yun-zhu,FU Li*,MAO Xi-guang.High risk factors affect sperm DNA integrity and progress on the detection techniques for sperm DNA integrity[J].Chinese Journal of Family Planning & Gynecotokology,2017,(1):29-32.
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影响精子DNA完整性高危因素及检测技术进展
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2017年1期
页码:
29-32
栏目:
综述
出版日期:
2017-01-25

文章信息/Info

Title:
High risk factors affect sperm DNA integrity and progress on the detection techniques for sperm DNA integrity
作者:
兰云竹1综述付莉1*毛熙光2审校
西南医科大学附属医院,1.生殖中心;2.妇产科
Author(s):
LAN Yun-zhu1 FU Li1*MAO Xi-guang2
1.Department of Reproductive Center,2.Department of Gynaecology and Obstetrics, Affiliated Hospital of Southwest Medical University,Luzhou Sichuan 646000,P.R.China
关键词:
精子DNA完整性染色体结构高危因素检测技术
Keywords:
sperm DNA integritychromosome structurehigh risk factorsdetection techniques
摘要:
人类精子保存并承载着父辈遗传信息,精液生成过程缜密有序,但易受机体内在因素及环境外在因素影响。普通精液常规结果波动较大,通过对精子DNA完整性的监测,为男性患者精液质量进行评估参考。现就影响精子DNA完整性高危因素及精子DNA检测技术进行综述。
Abstract:
ObjectiveHuman sperm preserve and carry the farthers’ genetic information.The generative process of semen is careful and orderly,but affected by internal factors and environment external factors. Routine results of semen are instable, the sperm DNA integrity monitoring can provide evaluation reference of semen quality.We summarized high risk factors affecting sperm DNA integrity and progress on the detection techniques for sperm DNA integrity.

参考文献/References:

[1]曾兰,叶飞,李运星,等精子 DNA 完整性与精液常规参数相关性分析 [J]中国计划生育和妇产科,2014,6(4):47-50 [2]DE Bantel-a, FLEURY-FEITH J, POIROT C, et al. Simultaneous vitality and DNA-fragmentation measurement in spermatozoa of smokers and non-smokers [J]. Cytometry. Part B, Clinical Cytometry, 2015, 88 (2) : 120-124. [3]杨雪梅,宋亚曼精液常规参数对精子核DNA完整性影响的初步探讨 [J]中国卫生检验杂志,2015,25(18):3113-3116 [4]魏任雄,王辉精浆弹性蛋白酶与精液常规参数及精子DNA完整性的相关性研究 [J]中华男科学杂志,2014,20(10):902-906 [5]焦瑞宝,冯恒孝,唐吉斌,等.不育患者精液的氧化应激对精子DNA完整性等参数的影响 [J].检验医学,2013,28(6):487-491. [6]赵永平,林典梁,张晓威,等精子细胞凋亡率与胚胎停育相关分析 [J]中国计划生育学杂志,2012,20(9):619-622 [7]Hikim AP, Lue Y, Yamamoto CM,et al. Key apoptotic pathways for heat-induced programmed germ cell death in the testis[J].Endocrinology,2003,144 (7):3167-3175. [8]乜照燕,吴海峰,张娜,等不同年龄对精子凋亡率及DNA完整性影响的研究 [J]中华男科学杂志,2012,18(11):1004-1008 [9]P Oger, C Yazbecle, Gervais, et al. Adverse effects of hepatitis B virus on sperm motility and fertilization ability during IVF [J]. Reprod biomed online, 2011, 23 (2) : 207-212. [10]Tong A,Gou L,Lau QC, et al.Proteomic profiling identifies aberrant epigenetic modifications induced by hepatitis B virus X protein[J]. Journal of proteome research,2009,8(2):1037-1046. [11]刘浩,耿春惠,王维,等乙肝病毒对人精液参数和精子DNA完整性的影响 [J]中华男科学杂志,2013,19(10):896-898 [12]赵一帆,任飞强,胡开妮,等.睡眠剥夺导致精子质量异常的可能机制探讨 [J]. 黑龙江医学,2015,39(10):1165-1166. [13]Methippara MM,Alam MN,Szymusiak R,et al.Preoptic Area Warming Inhibits Wake-active Neurons in the Perifornical Lateral Hypothalamus [J]. Brain Res,2003,960(960):165-173 [14]何泳志,李大文,何冰,等. 不育男性司机精液质量及精子DNA完整率与工作时间的关联性研究[J].中国临床新医学,2015,8 (6) :516-519. [15]Bujan L,Daudin M,Charlet JP,et al.Increase in Scrotal Temperature in Car Drivers. Hum Reprod [J],2000,15(6):1355-1357 [16]李强,崔向荣井宣,等. 吸烟对男性精液质量,精子DNA完整性及Chk1基因表达的影响 [J]生殖医学杂志,2015,24(12):1019-1024 [17]Yue M,Zeng L,Singh A,et al.Rad4 mainly functions in Chk1-mediated DNA damage checkpoint pathway as a scaffold protein in the fission yeast Schizosaccharomyces pombe [J].PLoS One,2014,9(3):434-438 [18]AL-KAABI M M, ALSHAREEDA A T, JERJEES D A, et al. Checkpoint kinase1 (CHK1) is an important biomarker in breast cancer having a role in chemotherapy response [J]. British Journal of Cancer, 2015, 112 (5): 901-911. [19]黄国泉血铅浓度对精子质量的影响探讨 [J]医学信息(上旬刊),2011,24(3):1585-1586 [20]邢德峰,任南琪,王爱杰FISH技术在微生物生态学中的研究及进展 [J]微生物学通报,2003,30 (5):114-119 [21]邱毅,张丽红,王磊光,等精子染色质扩散实验检测男性不育患者精子DNA碎片 [J]国际生殖健康/计划生育杂志,2008,27(6):387-389, 后插一 [22]OSTLING O, JOHANSON K J. Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells [J]. Biochemical and Biophysical Research Communications, 1984, 123 (1): 291-298. [23]陈建伟,张晓霞,崔云双尾彗星实验检测精子DNA完整性的方法学建立 [J]检验医学,2012,27(1):21-25

相似文献/References:

[1]曾兰,叶飞,李运星,等.精子DNA完整性与精液常规参数相关性分析[J].中国计划生育和妇产科,2014,(04):0.
 ZENG Lan,YE Fei,LI Yun-xing,et al.[J].Chinese Journal of Family Planning & Gynecotokology,2014,(1):0.

备注/Memo

备注/Memo:
基金项目:泸医附院(编号:2014-71号-17)
更新日期/Last Update: 2017-01-25