[1]朱学芳,刘娟*.米索前列醇与补佳乐合用治疗稽留流产的 临床疗效分析[J].中国计划生育和妇产科,2017,(3):72-74.
　ZHU Xue-fang,LIU Juan*.Clinical efficacy analysis of misoprostol combined with progynova in the treatment of missed abortion[J].Chinese Journal of Family Planning & Gynecotokology,2017,(3):72-74.
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米索前列醇与补佳乐合用治疗稽留流产的 临床疗效分析
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2017年3期
页码:
72-74
栏目:
论著与临床
出版日期:
2017-03-25

文章信息/Info

Title:
Clinical efficacy analysis of misoprostol combined with progynova in the treatment of missed abortion
作者:
朱学芳; 刘娟*
扬州市妇幼保健院计划生育科
Author(s):
ZHU Xue-fang; LIU Juan*
Department of Family Planning，Yangzhou Maternal and Child Care Service Centre，Yangzhou Jiangsu 225000，P.R.China
关键词:
米索前列醇; 补佳乐; 稽留流产
Keywords:
misoprostol; progynova; missed abortion
分类号:
R 714.21
摘要:
目的分析米索前列醇与补佳乐合用治疗稽留流产的临床疗效。方法选择扬州市妇幼保健院2013年2月至2016年1月收治的稽留流产患者90例作为研究对象，通过随机数字表法将其分为观察组和对照组各45例。观察组采用米索前列醇与补佳乐合用行清宫术，对照组采用米索前列醇与米非司酮合用行清宫术。记录两组患者的手术时间及术中出血量、总出血量、人工流产综合征发生率、再次清宫率、不良反应发生率，比较两种治疗方法的临床疗效。结果观察组治疗总有效率明显高于对照组（P<005）；观察组手术时间、术中出血量及总出血量明显少于对照组（P<005）；观察组人工流产综合征发生率及再次清宫率明显低于对照组（P<005）；两组不良反应发生率比较差异无统计学意义（P>005）。结论采用米索前列醇与补佳乐合用行清宫术治疗稽留流产患者的临床疗效显著，出血量少，具有较高的胚囊排出率，有效减少了二次清宫情况的发生，安全性高，患者恢复快，值得推广使用。
Abstract:
ObjectiveTo analyze the efficacy of combined use of misoprostol and progynova in treatment of patients with missed abortion. Methods90 patients with missed abortion in Yangzhou Maternal and Child Care Service Centre from February 2013 to January 2016 were selected according to random number table method.They were divided into observation group and control group,with 45 cases in each group.The observation group used misoprostol combined with progynova for curettage while the control group used misoprostol combined with mifepristone. The operation time, intraoperative blood loss, total bleeding volume, incidence of induced abortion syndrome, rate of re-curettage, rate of adverse reactions were recorded and clinical efficacy of the two treatments were compared. ResultsThe total effective rate of the observation group was significantly higher than that of the control group (P<0.05). The operation time, intraoperative blood loss and total bleeding were significantly less than those in the control group (P<005). The incidence of abortion syndrome and the rate of re-curettage were significantly lower in the observation group than in the control group (P<005).There was no significant difference in the incidence of adverse reactions between the two groups (P>005).ConclusionMisoprostol combined with progynova for curettage in the treatment of missed abortion has significant clinical efficacy.With less bleeding and higher embryo sac discharge rate, it effectively reduces the incidence of secondary curettage.It is worthy of clinical promotion because of high safety and fast patients recovery.

参考文献/References:

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备注/Memo

备注/Memo:
江苏省卫生计生委科研项目（项目编号：Z201524）
更新日期/Last Update: 2017-03-25