[1]李莉*,刘媛媛,邹佑军.卡前列甲酯栓联合缩宫素对瘢痕子宫剖宫产患者 产后出血的影响[J].中国计划生育和妇产科,2017,(2):33-35.
 LI Li*,LIU Yuan-yuan,ZOU You-jun.Effect of carboprost methylate suppository combined with oxytocin on postpartum hemorrhage in patients with scar uterus[J].Chinese Journal of Family Planning & Gynecotokology,2017,(2):33-35.
点击复制

卡前列甲酯栓联合缩宫素对瘢痕子宫剖宫产患者 产后出血的影响
分享到:

《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2017年2期
页码:
33-35
栏目:
论著与临床
出版日期:
2017-02-25

文章信息/Info

Title:
Effect of carboprost methylate suppository combined with oxytocin on postpartum hemorrhage in patients with scar uterus
作者:
李莉*刘媛媛邹佑军
深圳市龙华新区人民医院
Author(s):
LI Li* LIU Yuan-yuan ZOU You-jun
Department of Obstetrics, People’s Hospital of Longhua New District, Shenzhen Guangdong 518109,P.R.China
关键词:
卡前列甲酯栓缩宫素瘢痕子宫剖宫产产后出血
Keywords:
carboprost methylate suppositoryoxytocincesarean sectionpostpartum hemorrhage
分类号:
R 714.46+1
摘要:
目的探讨卡前列甲酯栓联合缩宫素对瘢痕子宫剖宫产患者产后出血的影响。方法 选择深圳市龙华新区人民医院2013年4月至2015年6月收治的200例瘢痕子宫产妇作为研究对象,其中单纯采用缩宫素预防治疗的为对照组,采用卡前列甲酯栓联合缩宫素进行预防产后出血治疗的为研究组,每组100例。统计分析两组术中、术后2 h、24 h出血量、第三产程时间及产后不良反应发生概率。结果研究组患者术中出血量、产后2 h出血量、产后24 h出血量、第三产程时间分别为(1746±285)mL、(1472±316)mL、(2501±543)mL、(723±101)min,均明显优于对照组[(2849±384)mL、(2414±458)mL、(3526±617)mL、(1391±052)min](P<005);两组产妇术后呕吐、面色潮红、腹泻、腹痛等不良反应发生率比较,差异无统计学意义(P>005);研究组产妇产后出血发生率 (400 %)显著低于对照组 (1300 %) (P<005)。结论卡前列甲酯栓联合缩宫素能明显促进子宫收缩,预防瘢痕子宫剖宫产产妇产后出血,且安全性较高,有很好的临床推广价值。
Abstract:
ObjectiveTo explore the effect of carboprost methylate suppository combined with oxytocin on postpartum hemorrhage in patients with scar uterus. Methods200 cases of pregnant women with scar uterus in People’s Hospital of Longhua New District from April 2013 to June 2015 were selected and divided into study group and control group,each group with 100 cases. Women in the control group were treated with oxytocin in the preventive treatment, women in the study group were using carboprost methylate suppository combined with oxytocin in the prevention and treatment of postpartum hemorrhage. Amount of bleeding during,2h and 24h after operation, third stage of labor time and adverse reactions postpartum of the two groups were compared. ResultsThe results showed that the amount of bleeding during,2h and 24h after operation,and the third stage of labor time in the study group [(1746 ± 285) mL,(1472±316) mL,(2501 ± 543) mL, (723 ± 101)min] were significantly better than the control group[(2849±384)mL、(2414±458)mL、(3526±617)mL、(1391±052)min].The differences were statistical significant (P< 005); the rate of adverse reactions such as vomiting, facial flushing, diarrhea and abdominal pain in the two groups after cesarean section had no statistical significance (P> 005); the incidence of postpartum hemorrhage in the study group was 4%, which was significantly lower than of the control group (13%) (P< 005).ConclusionCarboprost methylate suppository combined with oxytocin has a significant effect in promoting uterine contraction, and preventing postpartum hemorrhage in patients with scarred uterine, which is safe for clinical promotion.

参考文献/References:

[1]乔娟,漆洪波治疗产后出血的药物评价 [J]中华产科急救电子杂志,2014,3(4):240-243 [2]韦淑芬瘢痕子宫患者再次妊娠剖宫产产后出血的相关因素分析 [J]中国现代医生,2013,51(27):132-134 [3]Zhang Y,Li W,Yan T,et al. Early detection of lesions of dorsal artery of foot in patients with type 2 diabetes mellitus by high-frequency ultrasonography [J]. Huazhong Univ Sci Technolog Med Sci,2011,29 (3):387-390. [4]刘兴会,杨慧霞产后出血预防和处理措施评价 [J]中华围产医学杂志,2013,16 (8):449-451 [5]刘彩霞,王德智,李秀荞,等卡前列甲酯栓预防产后出血的临床研究 [J]中华妇产科杂志,1997,32 (1):22-24 [6]刘兴会,张力,张静《产后出血预防与处理指南(草案)》(2009)及《产后出血预防与处理指南(2014年版)》解读 [J]中华妇幼临床医学杂志(电子版),2015,11(4):433-447 [7]李丽娟,郭宏亮卡前列甲醋栓预防产后出血的临床观察 [J]中华妇幼临床医学杂志(电子版),2013,9(2):205-207 [8]张志敏,杨玉秀,张海娟,等瘢痕子宫再次妊娠分娩方式的探讨 [J]河北医科大学学报,2014,7(9):1067-1069 [9]魏文珠卡前列甲酯栓联合催产素防治高危产妇剖宫产术后出血的疗效观察 [J]海南医学,2011,22(12):64-65 [10]Malyszko J,Mechanism of endothelial dysfunction in chronic kidney disease [J]. Clinica Chimica Acta, 2010, 411(20): 1412- 1420. [11]陈玉佳,徐静卡前列甲酯栓预防剖宫产术后出血700例 [J].中国药业,2013,22(9):101-102 [12]夏熙云卡前列甲酯栓联合催产素对高危产妇剖宫产术后出血的预防效果 [J]河南医学高等专科学校学报,2015,11(2):196-197

相似文献/References:

[1]田婕,曹炳雁,周应桂,等.气囊仿生助产765例临床应用观察[J].中国计划生育和妇产科,2009,(05):0.
 TIAN Jie,CAO Bing-yan,ZHOU Ying-gui,et al.[J].Chinese Journal of Family Planning & Gynecotokology,2009,(2):0.
[2]王明玉,冯菊昌.缩宫素联合钙剂和米索前列醇预防及治疗产后出血的临床分析[J].中国计划生育和妇产科,2010,(03):0.
 WANG Ming-yu,FENG Ju-chang..[J].Chinese Journal of Family Planning & Gynecotokology,2010,(2):0.
[3]陈倩,段成城,全望华,等.欣母沛、葡萄糖酸钙和缩宫素联合预防剖宫产产后出血疗效观察[J].中国计划生育和妇产科,2010,(04):0.
 CHEN Qian,DUAN Cheng-cheng,QUAN Wang-hua,et al.[J].Chinese Journal of Family Planning & Gynecotokology,2010,(2):0.
[4]于长莉,王昊珏.应用益母草注射液联合缩宫素预防产后出血的临床分析[J].中国计划生育和妇产科,2012,(02):0.
 YU Chang-li,WU Hao-jue.[J].Chinese Journal of Family Planning & Gynecotokology,2012,(2):0.
[5]安黎明.卡前列甲酯栓用于绝经后妇女宫内节育器取出术的临床观察[J].中国计划生育和妇产科,2013,(04):0.
 AN Li-ming.[J].Chinese Journal of Family Planning & Gynecotokology,2013,(2):0.
[6]胡红梅,赵敏.子宫颈扩张双球囊在足月妊娠引产的临床疗效观察[J].中国计划生育和妇产科,2013,(04):0.
 HU Hong-mei,ZHAO Min.[J].Chinese Journal of Family Planning & Gynecotokology,2013,(2):0.
[7]任芳,史惠蓉,张瑞涛,等.卡前列素氨丁三醇在腹腔镜子宫肌瘤剔除术中的应用[J].中国计划生育和妇产科,2013,(04):0.
 REN Fang,SHI Hui-rong *,ZHANG Rui-tao,et al.[J].Chinese Journal of Family Planning & Gynecotokology,2013,(2):0.
[8]康琴兰.米索前列醇和缩宫素联合预防产后出血的临床研究[J].中国计划生育和妇产科,2013,(05):0.
 KANG Qin-lan,Zhonghua Road Community Health Centre of Anding District in Dingxi City,[J].Chinese Journal of Family Planning & Gynecotokology,2013,(2):0.
[9]黄娟,王思义,陈颖,等.COOK双球囊促宫颈成熟的临床研究[J].中国计划生育和妇产科,2014,(06):0.
 HUANG Juan,WANG Si-yi,CHEN Ying,et al.[J].Chinese Journal of Family Planning & Gynecotokology,2014,(2):0.
[10]杜彧华,张强.COOK宫颈球囊联合缩宫素促宫颈成熟引产的效果分析[J].中国计划生育和妇产科,2015,(05):0.
 DU Yu-hua,ZHANG Qiang,[J].Chinese Journal of Family Planning & Gynecotokology,2015,(2):0.

更新日期/Last Update: 2017-02-25