[1]张晗,刘方琮,蔡丽瑛*.子痫前期胎盘组织中氧化应激、热休克蛋白27和热休克转录因子1的表达及意义[J].中国计划生育和妇产科,2017,(8):21-22,38.
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子痫前期胎盘组织中氧化应激、热休克蛋白27和热休克转录因子1的表达及意义
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2017年8期
页码:
21-22,38
栏目:
综述
出版日期:
2017-08-25

文章信息/Info

作者:
张晗刘方琮蔡丽瑛*
哈尔滨医科大学第一附属医院妇产科
关键词:
子痫前期氧化应激热休克蛋白27热休克转录因子1
分类号:
R 714.24+4
摘要:
子痫前期(preeclampsia,PE)是妊娠期特有的一种以多脏器功能损害为主的疾病,以妊娠20周后高血压、水肿、蛋白尿为主要临床特征。关于PE的病因及发病机制至今仍未明确,目前大多数学者认为氧化应激与PE发病的关系密切。最新研究表明在氧化应激水平状态下,PE患者胎盘组织中热休克蛋白27及其热休克转录因子1的表达均有不同程度的升高,从而导致滋养细胞过度凋亡是PE发病的关键环节。

参考文献/References:

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更新日期/Last Update: 2017-08-25