[1]杨晓清.异位妊娠不同保守治疗方案的疗效对比[J].中国计划生育和妇产科,2017,(5):55-57.
 YANG Xiao-qing.Efficacy comparison of different conservative treatment schemes for ectopic pregnancy[J].Chinese Journal of Family Planning & Gynecotokology,2017,(5):55-57.
点击复制

异位妊娠不同保守治疗方案的疗效对比
分享到:

《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2017年5期
页码:
55-57
栏目:
论著与临床
出版日期:
2017-05-25

文章信息/Info

Title:
Efficacy comparison of different conservative treatment schemes for ectopic pregnancy
作者:
杨晓清
广元市妇幼保健院
Author(s):
YANG Xiao-qing
Guangyuan Maternal and Child Health Care Hospital, Guangyuan Sichuan 610021,P.R.China
关键词:
异位妊娠保守治疗方案不良反应
Keywords:
ectopic pregnancy conservative treatment protocol adverse reaction
分类号:
R 714.22
摘要:
目的探讨不同保守治疗方案治疗异位妊娠的疗效及不良反应。方法回顾性分析2014年1月至2016年10月于广元市妇幼保健院就诊且采取药物保守治疗的249例异位妊娠患者的病例资料。根据治疗方案将患者分为5组:米非司酮组、甲氨蝶呤组、宫外孕I号方组、宫外孕I号方+甲氨蝶呤组和宫外孕I号方+米非司酮组。分析不同药物治疗方案的疗效和不良反应。结果5组的有效率分别为667 %、745 %、806 %、875 %和837 %,各组的人绒毛膜促性腺激素(human chorionic gonadotropin,h
Abstract:
ObjectiveTo explore the efficacy and side effects of different conservative treatment regimens for ectopic pregnancy.MethodsRetrospective analysis of the efficacy and side effects of different conservative treatment regimens for 249 ectopic pregnancy treated in Guangyuan Maternal and Child Health Care Hospital from January 2014 to October 2016.The patients were divided into five groups according to the treatment regimens : mifepristone group, methotrexate group, ectopic pregnancy prescription I group, ectopic pregnancy prescription I + methotrexate group and ectopic pregnancy prescription I + mifepristone group.ResultsThe effective rates were 667%, 745%, 806%, 875% and 837%;The median negative time of human chorionic gonadotropin(hCG) were (187±69)d,(142±52)d,(139±54)d,(108±49)d and (121±53)d; The incidence of adverse reactions in each group was 156%, 235%, 56%, 377% and 286%.The differences between the five groups in efficiency, median negative time and adverse reactions were statistically significant(P<005).ConclusionEctopic pregnancy prescription I has good therapeutic effect,with relatively short blood hCG negative time and minimal adverse reaction.

参考文献/References:

[1]SURAMPUDI K, GUNDABATTULA S RThe role of serum beta hCG in early diagnosis and management strategy of ectopic pregnancy [J]. Journal of Clinical and Diagnostic Research : JCDR, 2016, 10 (7): QC08-QC10. [2]HAMZA A, MEYBERG-SOLOMAYER G, JUHASZ-BSS I, et al. Diagnostic methods of ectopic pregnancy and early pregnancy loss: a review of the literature [J]. Geburtshilfe und Frauenheilkunde, 2016, 76(4): 377-382. [3]Barash JH,Buchanan EM,Hillson C. Diagnosis and management of ectopic pregnancy [J].Am Fam Physician,2014,90 (1):34-40. [4]MARRET H, FAUCONNIER A, DUBERNARD G, et al. Overview and guidelines of off-label use of methotrexate in ectopic pregnancy: report by CNGOF [J]. European Journal of Obstetrics & Gynecology and Reproductive Biology, 2016,154 (205): 105-109. [5]ELIK H, TOSUN M, ISIK Y, et al. The role of early determination of β-human chorionic gonadotropin levels in predicting the success of single-dose methotrexate treatment in ectopic pregnancy [J]. Ginekologia Polska, 2016, 87(7): 484-487. [6]ALSAMMANI M A, MOONA N A. Predictors of success of a Single-Dose methotrexate in the treatment of ectopic pregnancy [J]. Journal of Obstetrics and Gynaecology of India, 2016, 66(4): 233-238. [7]GMEZ GARCA M T, RUIZ SNCHEZ E, AGUARN BENTEZ G, et al. Caesarean scar ectopic pregnancy successfully treated with methotrexate and mifepristone [J]. Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology, 2015, 35(1): 105-106. [8]OHANNESSIAN A, CROCHET P, COURBIERE B, et al. Methotrexate treatment for ectopic pregnancy after assisted reproductive technology: A case-control study [J]. Gynecologie Obstetrique & Fertilite, 2016, 44(6): 341-344. [9]SAADATI N, NAJAFIAN M, MASIHI S, et al. Comparison of two different protocols of methotrexate therapy in medical management of ectopic pregnancy [J]. Iranian Red Crescent Medical Journal, 2015, 17(12): e20147. [10]MIRBOLOUK F, YOUSEFNEZHAD A, GHANBARI A. Predicting factors of medical treatment success with single dose methotrexate in tubal ectopic pregnancy: a retrospective study [J]. Iranian Journal of Reproductive Medicine, 2015, 13(6): 351-354. [11]GMEZ G M, AGUARN B G, BARBER B B, et al. Medical therapy(methotrexate and mifepristone) alone or in combination with another type of therapy for the management of cervical or interstitial ectopic pregnancy [J]. European Journal of Obstetrics, Gynecology, and Reproductive Biology, 2012, 165(1): 77-81. [12]VEENA P. Use of mifepristone along with methotrexate in medical management of unruptured ectopic pregnancy [J]. Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology, 2011, 31(7): 667. [13]Shrestha E,Yang Y,Li X,et al.Successful Conservative Management With Methotrexate and Mifepristone of Cervical Pregnancy [J].The Journal of Biomedical Research,2011,25(1):71-73.

相似文献/References:

[1]许瑞群.甲氨蝶呤联合米非司酮治疗异位妊娠134例疗效观察[J].中国计划生育和妇产科,2009,(06):0.
 XU Rui-qun.[J].Chinese Journal of Family Planning & Gynecotokology,2009,(5):0.
[2]王丽,方妍萍.腹腔镜手术治疗异位妊娠47例临床分析[J].中国计划生育和妇产科,2009,(06):0.
 WANG Li,FANG Yan-ping.[J].Chinese Journal of Family Planning & Gynecotokology,2009,(5):0.
[3]熊小娟.甲氨蝶呤联合米非司酮及大黄、芒硝外敷治疗异位妊娠探讨[J].中国计划生育和妇产科,2010,(05):0.
 XIONG Xiao-Juan.[J].Chinese Journal of Family Planning & Gynecotokology,2010,(5):0.
[4]李改珍,张露平,冯力民,等.双侧输卵管同时妊娠1例[J].中国计划生育和妇产科,2010,(05):0.
[5]文怡,石玲.输卵管切除术后间质部残端妊娠2例分析[J].中国计划生育和妇产科,2012,(04):0.
[6]蒋小琴,韩艳梅.胎盘植入保守治疗2例[J].中国计划生育和妇产科,2012,(06):0.
[7]唐超人,韩宇春,马双凤,等.血清β-HCG、孕酮水平在早期异位妊娠诊断中的应用[J].中国计划生育和妇产科,2014,(02):0.
 TANG Chao-ren,HAN Yu-chun,MA Shuang-feng,et al.[J].Chinese Journal of Family Planning & Gynecotokology,2014,(5):0.
[8]付丽,王祥燕.人工流产术后残留保守治疗效果的影响因素[J].中国计划生育和妇产科,2015,(02):0.
 FU Li,WANG Xiang-yan,[J].Chinese Journal of Family Planning & Gynecotokology,2015,(5):0.
[9]陈静,邱骏,滕银成,等.异位妊娠与避孕方法使用的相关性分析[J].中国计划生育和妇产科,2015,(05):0.
 CHEN Jing,QIU Jun,TENG Yin-cheng,et al.[J].Chinese Journal of Family Planning & Gynecotokology,2015,(5):0.
[10]梁春燕,黄艳萍,刘志玲,等.子宫动脉栓塞术联合局部化疗对剖宫产瘢痕妊娠的临床疗效研究[J].中国计划生育和妇产科,2015,(05):0.
 LIANG Chun-yan,HUANG Yan-ping,LIU Zhi-ling,et al.[J].Chinese Journal of Family Planning & Gynecotokology,2015,(5):0.

更新日期/Last Update: 2017-05-25