参考文献/References:
[1]郑晓娟,邓晓莉,刘湘源.54例抗磷脂综合征患者的妊娠结局[J].北京大学学报(医学版),2014,46(2):323-328.
[2]吴庆军,朱燕林,唐福林.抗磷脂综合征100例临床特征分析[J].中华风湿病学杂志,2007,11(11):675-678.
[3]ERKAN D, SALMON J E.The role of complement inhibition in thrombotic angiopathies and antiphospholipid syndrome [J].Turkish Journal of Haematology : Official Journal of Turkish Society of Haematology, 2016, 33(1): 1-7
[4]VAN DEN HOOGEN L L, VAN ROON J A, RADSTAKE T R, et al.Delineating the deranged immune system in the antiphospholipid syndrome [J].Autoimmunity Reviews, 2016, 15(1): 50-60.
[5]MEKINIAN A, BOURRIENNE M C, CARBILLON L, et al.Non-conventional antiphospholipid antibodies in patients with clinical obstetrical APS: Prevalence and treatment efficacy in pregnancies[J].Seminars in Arthritis and Rheumatism, 2016, 46(2): 232-237.
[6]SANMARCO M, BOFFA M C.Antiphosphatidylethanolamine antibodies and the antiphospholipid syndrome [J].Lupus, 2009, 18(10): 920-923.
[7]SUGI T.Kininogen-dependent antiphosphatidylethanolamine antibodies and autoantibodies to factor XII in patients with recurrent pregnancy losses[J].The Journal of Obstetrics and Gynaecology Research, 2013, 39(7): 1223-1229.
[8]SATO Y, SUGI T, SAKAI R.Autoantibodies to factor XII and Kininogen-Dependent antiphosphatidylethanolamine antibodies in patients with recurrent pregnancy loss augment platelet aggregation[J].American Journal of Reproductive Immunology (New York, N.Y.: 1989), 2015, 74(3): 279-289.
[9]SANMARCO M, ALESSI M C, HARLE J R, et al.Antibodies to phosphatidylethanolamine as the only antiphospholipid antibodies found in patients with unexplained thromboses [J].Thrombosis and Haemostasis, 2001, 85(5): 800-805.
[10]GRIS J C, QUR I, SANMARCO M, et al.Antiphospholipid and antiprotein syndromes in non-thrombotic, non-autoimmune women with unexplained recurrent primary early foetal loss.The Nimes Obstetricians and Haematologists Study——NOHA[J].Thrombosis and Haemostasis, 2000, 84(2): 228-236.
[11]SUGI T, KATSUNUMA J, IZUMI S, et al.Prevalence and heterogeneity of antiphosphatidylethanolamine antibodies in patients with recurrent early pregnancy losses[J].Fertility and Sterility, 1999, 71(6): 1060-1065.
[12]SUGI T, MATSUBAYASHI H, INOMO A, et al.Antiphosphatidylethanolamine antibodies in recurrent early pregnancy loss and mid-to-late pregnancy loss [J].The Journal of Obstetrics and Gynaecology Research, 2004, 30(4): 326-332.
[13]BLANK M, SHOENFELD Y.Antiphospholipid antibody-mediated reproductive failure in antiphospholipid syndrome[J].Clinical Reviews in Allergy & Immunology, 2010, 38(2/3): 141-147.
[14]BERTOLACCINI M L, GOMEZ S, PAREJA J F, et al.Antiphospholipid antibody tests: spreading the net [J].Annals of the Rheumatic Diseases, 2005, 64(11): 1639-1643.
[15]BERTOLACCINI M L, AMENGUAL O, ANDREOLI L, et al.14th international congress on antiphospholipid antibodies task force.report on antiphospholipid syndrome laboratory diagnostics and trends[J].Autoimmunity Reviews, 2014, 13(9): 917-930.
[16]IGON P, PERDAN PIRKMAJER K, TOMIC M, et al.Anti-phosphatidylserine/prothrombin antibodies are associated with adverse pregnancy outcomes [J].Journal of Immunology Research, 2015: 975704.
[17]BERTOLACCINI M L, ATSUMI T, KOIKE T, et al.Antiprothrombin antibodies detected in two different assay systems.Prevalence and clinical significance in systemic lupus erythematosus [J].Thrombosis and Haemostasis, 2005, 93(2): 289-297.
[18]ZIGON P, CUCNIK S, AMBROZIC A, et al.Detection of antiphosphatidylserine/prothrombin antibodies and their potential diagnostic value [J].Clinical & Developmental Immunology, 2013: 724592.
[19]ZHU Lei, LI Chun, LIU Na, et al.Diagnostic value of antibodies to phosphatidylserine/prothrombin complex for antiphospholipid syndrome in Chinese patients [J].Clinical Rheumatology, 2017, 36(2): 401-406.
[20]AMENGUAL O, FORASTIERO R, SUGIURA-OGASAWARA M, et al.Evaluation of phosphatidylserinedependent antiprothrombin antibody testing for the diagnosis of antiphospholipid syndrome: results of an international multicentre study [J].Lupus, 2017, 26(3): 266-276.
[21]ESPOSITO G, TAMBY M C, CHANSEAUD Y, et al.Anti-annexin V antibodies: are they prothrombotic?[J].Autoimmunity Reviews, 2005, 4(1): 55-60.
[22]BECAREVIC M.The IgG and IgM isotypes of anti-annexin A5 antibodies: relevance for primary antiphospholipid syndrome [J].Journal of Thrombosis and Thrombolysis, 2016, 42(4): 552-557.
[23]IRMAN S, SKARABOT M, MUEVIC I, et al.The use of atomic force microscopy to study the pathologic effects of anti-annexin autoantibodies[J].Journal of Autoimmunity, 2011, 36(2): 98-105.
[24]BIZZARO N, TONUTTI E, VILLALTA D, et al.Prevalence and clinical correlation of antiphospholipidbinding protein antibodies in anticardiolipin-negative patients with systemic lupus erythematosus and women with unexplained recurrent miscarriages[J].Archives of Pathology & Laboratory Medicine, 2005, 129(1): 61-68.
[25]ARNOLD J, HOLMES Z, PICKERING W, et al.Anti-beta 2 glycoprotein 1 and anti-annexin V antibodies in women with recurrent miscarriage[J].British Journal of Haematology, 2001, 113(4): 911-914.
[26]BECAREVIC M, STOJANOVIC L, IGNJATOVIC S, et al.The IgM isotype of anti-annexin A5 antibodies and multiple positivity of conventional antiphospholipid antibodies: increasing the number of clinical manifestations of primary antiphospholipid syndrome [J].Clinical Rheumatology, 2016, 35(5): 1361-1365.
[27]ZHANG Shulan, WU Ziyan, LI Jing, et al.Evaluation of the clinical relevance of anti-annexin-A5 antibodies in Chinese patients with antiphospholipid syndrome [J].Clinical Rheumatology, 2017, 36(2): 407-412.
[28]SALLE V, SCHMIDT J, SMAIL A, et al.Antibodies directed against annexin A2 and obstetric morbidity[J].Journal of Reproductive Immunology, 2016, 118: 50-53.
[29]PERICLEOUS C, RUIZ-LIMN P, ROMAY-PENABAD Z, et al.Proof-of-concept study demonstrating the pathogenicity of affinity-purified IgG antibodies directed to domain I of β2-glycoprotein I in a mouse model of anti-phospholipid antibody-induced thrombosis [J].Rheumatology (Oxford, England), 2015, 54(4): 722-727.
[30]IOANNOU Y, ROMAY-PENABAD Z, PERICLEOUS C, et al.In vivo inhibition of antiphospholipid antibody-induced pathogenicity utilizing the antigenic target peptide domain I of beta2-glycoprotein I: proof of concept [J].Journal of Thrombosis and Haemostasis : JTH, 2009, 7(5): 833-842.
[31]AGOSTINIS C, DURIGUTTO P, SBLATTERO D, et al.A non-complement-fixing antibody to β2 glycoprotein I as a novel therapy for antiphospholipid syndrome[J].Blood, 2014, 123(22): 3478-3487.
[32]DE LAAT B, WU Xiao-xuan, VAN LUMMEL M, et al.Correlation between antiphospholipid antibodies that recognize domain I of beta2-glycoprotein I and a reduction in the anticoagulant activity of annexin A5[J].Blood, 2007, 109(4): 1490-1494.
[33]DE CRAEMER A S, MUSIAL J, DEVREESE K M.Role of anti-domain 1-β2 glycoprotein I antibodies in the diagnosis and risk stratification of antiphospholipid syndrome [J].Journal of Thrombosis and Haemostasis : JTH, 2016, 14(9): 1779-1787.
[34]DE LAAT B, PENGO V, PABINGER I, et al.The association between circulating antibodies against domain I of beta2-glycoprotein I and thrombosis: an international multicenter study[J].Journal of Thrombosis and Haemostasis : JTH, 2009, 7(11): 1767-1773.
[35]MONTALVO S, ELDIO P S, DA SILVA SARAIVA S, et al.Clinical implications of the detection of antibodies directed against domain 1 of β2-glycoprotein 1 in thrombotic antiphospholipid syndrome [J].Thrombosis Research, 2016, 148: 32-37.
[36]MARCHETTI T, DE MOERLOOSE P, GRIS J C.Antiphospholipid antibodies and the risk of severe and non-severe pre-eclampsia: the NOHA case-control study[J].Journal of Thrombosis and Haemostasis : JTH, 2016, 14(4): 675-684.
[37]MURTHY V, WILLIS R, ROMAY-PENABAD Z, et al.Value of isolated IgA anti-β2 -glycoprotein I positivity in the diagnosis of the antiphospholipid syndrome[J].Arthritis and Rheumatism, 2013, 65(12): 3186-3193.
[38]RUIZ-GARCA R, SERRANO M, MARTNEZ-FLORES J , et al.Isolated IgA anti- β2 glycoprotein I antibodies in patients with clinical criteria for antiphospholipid syndrome[J].Journal of Immunology Research, 2014 (2014): 704395.
[39]LEE R M, BRANCH D W, SILVER R M.Immunoglobulin a anti-beta2-glycoprotein antibodies in women who experience unexplained recurrent spontaneous abortion and unexplained fetal death [J].American Journal of Obstetrics and Gynecology, 2001, 185(3): 748-753.
[40]YAMADA H, TSUTSUMI A, ICHIKAWA K, et al.IgA-class anti-beta2-glycoprotein I in women with unexplained recurrent spontaneous abortion[J].Arthritis and Rheumatism, 1999, 42(12): 2727-2728.