[1]董英辉,段亚男,白文彩,等.高强度聚焦超声治疗子宫肌瘤[J].中国计划生育和妇产科,2012,(05):0.
　DONG Ying-hui,DUAN Ya-nan,BAI Wen-cai,et al.[J].Chinese Journal of Family Planning & Gynecotokology,2012,(05):0.
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高强度聚焦超声治疗子宫肌瘤
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2012年05期
页码:
0
栏目:
论著与临床
出版日期:
2012-10-30

文章信息/Info

作者:
董英辉; 段亚男; 白文彩; 张献波
石家庄市第一医院肿瘤一科；邢台宁晋县医院妇产科；
Author(s):
DONG Ying-hui1; DUAN Ya-nan1; BAI Wen-cai2; ZHANG Xian-bo1 1.
Department of Oncology,Shijiazhuang the 1st hospital,Shijiazhuang Hebei 050011,P.R.China,2.Department of Gynecology and Obstetrics,Ninjing County Hospital in Xingtai,Xingtai Hebei 055550,P.R.China
关键词:
高强度聚焦超声; 子宫肌瘤; 治疗功率; 疗效
分类号:
R737.33
摘要:
目的评价高强度聚焦超声(High-intensity focused ultrasound,HIFU)治疗子宫肌瘤的疗效及安全性。方法对拒绝手术要求保留子宫的单发或多发性子宫肌瘤患者58例,采用JC200型高强度聚焦超声治疗系统,在B超定位并监视下,从体外对肌瘤进行HIFU治疗。治疗后1d、3～6个月随访观察患者临床症状、体征及瘤体影像学变化,对疗效作出评估。结果 16例患者术后1d行盆腔MRI显示子宫肌瘤组织表现为凝固性坏死,51例患者3～6个月后经量增多、经期延长症状改善,B超检查肌瘤回声增强,肌瘤血流明显减少,肌瘤体积较前缩小。58例患者HIFU治疗后近期总有效率为87.93%(疗效显著18例、有效33例),无效7例(12.07%)。依据治疗功率进行分层分析,低功率组(<300w)的平均治疗时间5.04h,明显多于高功率组(>300 w)3.10h(P<0.05),两组的有效率分别为88.6%和86.9%,差异无统计学意义(P>0.05)。结论 HIFU治疗子宫肌瘤是一种安全有效的非手术治疗方法,对于耐受性差的患者,采用低功率仍可取得一定的效果。

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更新日期/Last Update: 2012-10-30