[1]张儒英,苏日娜.白血病抑制因子在稽留流产中的表达[J].中国计划生育和妇产科,2013,(05):0.
 ZHANG Ru-ying,SU Ri-na,[J].Chinese Journal of Family Planning & Gynecotokology,2013,(05):0.
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白血病抑制因子在稽留流产中的表达
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2013年05期
页码:
0
栏目:
论著与临床
出版日期:
2013-10-31

文章信息/Info

作者:
张儒英苏日娜
内蒙古医科大学附属医院妇产科;
Author(s):
ZHANG Ru-ying;SU Ri-na;
Department of Obstetrics and Gynecology,The Affiliated Hospital of Inner Monglia Medical College;
关键词:
稽留流产白血病抑制因子子宫内膜容受性
分类号:
R714.21
摘要:
目的探讨白血病抑制因子(leukemia inhibitory factor,LIF)的表达与稽留流产的关系。方法选择30例稽留流产患者为观察组,同期自愿选择人工流产术终止妊娠的正常早孕妇女30例为对照组,用免疫组化链酶素抗生物蛋白—过氧化物酶连接(streptavidin-perosidase,SP)法检测LIF在两组绒毛及蜕膜组织中的表达情况。结果①LIF在绒毛组织中表达于滋养细胞胞浆中;在蜕膜组织中表达于腺体细胞胞浆。②LIF在两组蜕膜组织中的表达均明显高于绒毛组织,差异有统计学意义(P<0.05)。③LIF在观察组绒毛及蜕膜组织中的表达较对照组明显降低,差异有统计学意义(P<0.05)。结论 LIF在绒毛及蜕膜组织中的表达强度降低,胚胎着床后发育不良导致稽留流产。

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更新日期/Last Update: 2013-10-30