[1]朱烨.原因不明自然流产相关因素分析[J].中国计划生育和妇产科,2017,(10):21-24.
　ZHU Ye.Analysis of related factors of unexplained spontaneous abortion[J].Chinese Journal of Family Planning & Gynecotokology,2017,(10):21-24.
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原因不明自然流产相关因素分析
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2017年10期
页码:
21-24
栏目:
论著与临床
出版日期:
2017-10-25

文章信息/Info

Title:
Analysis of related factors of unexplained spontaneous abortion
作者:
朱烨
西安第五人民医院妇产科
Author(s):
ZHU Ye
Department of Obstetrics and Gynecology, Xi'an Fifth People's Hospital, Xi'an Shaanxi 70012, P.R.China
关键词:
原因不明自然流产; 相关因素
Keywords:
unexplained spontaneous abortion;  related factors
分类号:
R 714.21
摘要:
目的分析原因不明自然流产(unexplained spontaneous abortion,USA)的相关因素。 方法选取2015年1月至2016年2月在西安第五人民医院就诊的孕早期妇女1 045例为观察对象，统计其年龄、文化程度、既往孕产史等资料，进行单因素分析后经多因素Logistic回归分析USA的危险因素。 结果单因素研究分析发现年龄、文化程度、既往孕次、既往胎次、自然流产史、人工流产史、怀孕季节、产前体质量指数(body mass index, BMI)、围孕期服用叶酸、血清同型半胱氨酸(homocysteine,Hcy)水平、血清叶酸等对USA的发生有显著影响(P<005 )。多因素分析结果显示，自然流产史、人工流产史、既往胎次、孕前BMI偏低、文化程度、年龄及孕期服用叶酸、高Hcy血症、血清叶酸高水平与USA的发生有统计学关联(P<005 ) ，OR值分别为12180、10988、6448、2109、1749、1054、0629、2598、0237。其中，围孕期服用叶酸和血清叶酸高水平是降低孕妇USA发生率的有利因素。 结论孕妇年龄＞30岁，文化程度较低，有自然流产史，有人工流产史、孕前BMI过低，血清Hcy水平较高，血清叶酸水平较低易发生USA。
Abstract:
ObjectiveTo analyze related factors of unexplained spontaneous abortion(USA). MethodsA total of 1 045 pregnant women were selected as observation object in Xi'an Fifth People 's Hospital from January 2015 to February 2016. Statistics of their age, education level, history of previous pregnancy and other information were collected , risk factors of USA were analyzed by single factor analysis and multivariate logistic regression. ResultsThe single factor analysis showed that pregnancy, history of spontaneous abortion and artificial abortion,prenatal BMI, gestational folic acid, serum Hcy and serum folic acid had a significant impact on the occurrence of USA(P<005). After analysis of multivariate analysis, the results showed that the history of spontaneous abortion and artificial abortion, previous parity, prepregnancy low body weight, education level, age and pregnancy taking folic acid, high Hcy hyperlipidemia, serum folic acid levels were statistically correlated with the incidence of USA (P<005). OR values were 12180,10988,6448,2109,1749,1054,0629 and 2598,0237 respectively. Among them, the perinatal taking folic acid and high levels of serum folic acid were favorable factors in reducing the incidence of USA in pregnant women. ConclusionPregnant women who are over 30 years of age,with low educational level, a history of spontaneous or artificial abortion, low prenatal BMI, high serum Hcy level and low serum folic acid level were prone to spontaneous abortion.

参考文献/References:

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更新日期/Last Update: 2017-10-25