[1]徐晓楠*,朱娟,黄燕媚,等.妊娠期尿路感染病原菌分布、临床防治及危险因素分析[J].中国计划生育和妇产科,2018,(6):48-50,59.
　XU Xiao-nan*,ZHU Juan,HUANG Yan-mei,et al.Analysis of pathogen distribution, clinical prevention and risk factors of urinary tract infection in pregnancy[J].Chinese Journal of Family Planning & Gynecotokology,2018,(6):48-50,59.
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妊娠期尿路感染病原菌分布、临床防治及危险因素分析
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2018年6期
页码:
48-50,59
栏目:
论著与临床
出版日期:
2018-06-25

文章信息/Info

Title:
Analysis of pathogen distribution, clinical prevention and risk factors of urinary tract infection in pregnancy
作者:
徐晓楠1*; 朱娟2; 黄燕媚1; 钟碧茹1
1.514100广东梅州,蕉岭县人民医院产科；2.510010广东广州，广东省妇幼保健院产前诊断中心
Author(s):
XU Xiao-nan1*；ZHU Juan2；HUANG Yan-mei1；ZHONG Bi-ru1
1.Department of Obstetrics,Jiao Lin People's Hospital,Meizhou Guangdong 514100；2.Prenatal Diagnosis Center,Guangdong Women and Children Hospital，Guangzhou Guangdong 510010，P.R.China
关键词:
妊娠; 尿路感染; 危险因素
Keywords:
pregnancy; urinary tract infection; risk factors
分类号:
R 6951
摘要:
目的分析孕妇尿路感染(urinary tract infection，UTI)的危险因素、病原菌种类分布、敏感抗生素，为妊娠期UTI的防治提供依据。方法选取2013年1月至2015年1月在广东省妇幼保健院产检的111例妊娠合并UTI孕妇为感染组，对其中段尿标本进行细菌培养,分析病原菌的种类和分布；采用病例对照研究方法随机选取我院同期产检无UTI的孕妇135例为对照组，对两组孕妇进行问卷调查和病历摘录,采用logistic回归模型分析UTI发生的危险因素。结果感染组中革兰阴性菌占622 ％，革兰阳性菌占351 ％，真菌27 %；其中大肠埃希菌检出率最高（468 %），其次为金黄色葡萄球菌（251 %）；大肠埃希菌对青霉素类、红霉素、四环素耐药率较高，对呋喃妥因、诺氟沙星、头孢曲松、庆大霉素敏感；孕妇贫血、流产史、阴道炎、泌尿系统结石是妊娠期UTI的高危因素。结论UTI孕妇的主要病原菌为革兰阴性菌，应注意妊娠期UTI的高危因素，根据孕妇病情合理选择敏感抗菌药物及时治疗。
Abstract:
ObjectiveTo andyze the risk factors，the main pathogens and antibiotic sensitivity of urinary tract infection(UTI) during pregnancy to improve the diagnostic level and therapeutic effect．MethodsIn a retrospective study，111 pregnant women with UTI in Guangdong Women and Children Hospital from January 2013 to January 2015 were enrolled，and urine culture and drug sensitivity test were analyzed．135 pregnant women without UTI in the maternity clinic were selected as control group. Used Chi-square test to select the risk factors for UTI. Applicated non-conditional Logistic regression further filter the main risk factors for UTI．Results111 cases of UTI in pregnant women with gram-negative bacteria (622 %), gram positive bacteria accounted for 351 %, fungal infection accounted for 27 %; the highest rate of e. coli (468 %), followed by staphylococcus aureus accounted for 251 %. The e.coli was more resistant to penicillin, erythromycin, tetracycline and sensitive to nitrofurantoin, norfloxacin,ceftriaxone, gentamycin.Pregnant women hemoglobin levels, history of abortion, vaginitis, urinary calculi were risk factors of UTI during pregnancy. ConclusionThe main pathogenic bacteria in UTI in pregnant women is gram-negative bacteria.We should pay attention to the risk factors of UTI during pregnancy, according to the pregnant women’s condition to select sensitive antimicrobial treatment in a timely manner.

参考文献/References:

［1］那彦群，叶章群，孙颖浩，等．2014版中国泌尿外科疾病诊断治疗指南:泌尿系统感染诊断治疗 ［M］．北京：人民卫生出版社，2014：424-434． ［2］KNOWLES S J, O'SULLIVAN N P, MEENAN A M, et al. Maternal sepsis incidence,aetiology and outcome for mother and fetus:a prospective study ［J］. BJOG： an International Journal of Obstetrics and Gynaecology, 2015, 122(5): 663-671. ［3］倪英，尉晨，李光辉，等．医院获得性尿路感染的病原菌分布及危险因素Logistic回归分析 ［J］．中华医院感染学杂志，2011，21（17）：3622-3624． ［4］杨慧霞，狄文．妇产科学(国家卫计委住院医规培教材) ［M］．北京：人民卫生出版社，2016：161-164． ［5］Jyothiprakashraju，Radhika，Bala Chandrasekhar.Bacterial profile and drug susceptibility pattern of urinary tract infection in pregnant women at University of Gondar Teaching Hospital Northwest Ethiopia ［J］．BMC Research Notes，2012（5）：197． ［6］Meher Rizvi，F Khan, I Shukla, et al.Rising prevalence of antimicrobial resistance in urinary tract infections during pregnancy: Necessity for exploring newer treatment options［J］．Journal of Laboratory Physicians，2011，3(2):98-103.

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更新日期/Last Update: 2018-06-25