[1]郭艳艳*,王秀妹.抗苗勒管激素水平作为卵巢子宫内膜异位囊肿 剥除术后评价卵巢早衰指标的应用价值分析[J].中国计划生育和妇产科,2018,(8):54-56.
　GUO Yan-yan*,WANG Xiu-mei.Analysis of the clinical value of anti-Mullerian hormone level as an indicator of premature ovarian failure after enucleation of ovarian endometriosis cyst[J].Chinese Journal of Family Planning & Gynecotokology,2018,(8):54-56.
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抗苗勒管激素水平作为卵巢子宫内膜异位囊肿 剥除术后评价卵巢早衰指标的应用价值分析
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2018年8期
页码:
54-56
栏目:
论著与临床
出版日期:
2018-08-25

文章信息/Info

Title:
Analysis of the clinical value of anti-Mullerian hormone level as an indicator of premature ovarian failure after enucleation of ovarian endometriosis cyst
作者:
郭艳艳*; 王秀妹
海口市妇幼保健院妇产科
Author(s):
GUO Yan-yan*;  WANG Xiu-mei
Department of Gynecology and Obstetrics, Maternal and Child Health Care Hospital of Haikou, Haikou Hainan 570102, P.R.China
关键词:
卵巢子宫内膜异位症; 囊肿; 卵巢早衰; 抗苗勒管激素
Keywords:
ovarian endometriosis;  cysts;  premature ovarian failure;  anti-Mullerian hormone
分类号:
R 71171
摘要:
目的分析抗苗勒管激素（anti-Mullerian hormone，AMH）水平作为卵巢子宫内膜异位囊肿剥除术后评价卵巢早衰指标的应用价值。方法选取2015～2016年海口市妇幼保健院收治的76例卵巢子宫内膜异位囊肿患者为研究对象，所有患者均行囊肿剥除术治疗。于术前及术后1～3月分别检测血清AMH水平、卵巢储备功能指标［血清卵泡刺激素（follicle stimulating hormone，FSH）、雌二醇（estradiol，E2）］及双侧卵泡数量，分析患者血清AMH与患者术后卵巢早衰、卵泡数量、妊娠率的关系。结果卵巢子宫内膜异位囊肿剥除术后，患者血清AMH水平较治疗前下降（P<005）；有25例患者发生卵巢早衰（3289 %），其平均血清AMH水平、E2水平低于未发生卵巢早衰患者，FSH水平高于未发生卵巢早衰患者，差异均有统计学意义（P<005）；双侧窦状卵泡数量≥10个组患者平均血清AMH水平高于<10个组患者（P<005）；妊娠成功组患者的平均血清AMH水平高于妊娠失败组患者（P<005）。结论卵巢子宫内膜异位囊肿剥除术后患者的血清AMH水平与卵巢储备功能、卵泡数量及妊娠率密切相关，可作为评价卵巢早衰的重要参考指标。
Abstract:
ObjectiveTo analyze the clinical value of anti-Mullerian hormone(AMH）level as an indicator of premature ovarian failure after enucleation of ovarian endometriosis cyst. MethodsA retrospective study of 76 cases of ovarian endometriosis from 2015 to 2016 in Maternal and Child Health Care Hospital of Haikou was conducted. All patients were treated with cystectomy. Serum AMH levels, indicators of ovarian reserve ［follicle stimulating hormone (FSH), estradiol (E2)］ and the number of bilateral follicles preoperative and postoperative 1 ~ 3 months were detected,and analyzed the relationship between serum AMH and premature ovarian failure（POF）, follicle number, pregnancy rate after operation. ResultsAfter the operation of ovarian endometriosis cyst, the serum AMH level of 76 cases was lower than that before treatment (P<005).A total of 25 patients with premature ovarian failure, the incidence rate was 3289 %; their mean serum AMH level and E2 was lower，FSH was higher than those of non-POF group，the differences were statistically significant (P<005). Mean serum AMH levels in patients with bilateral antral follicles≥ 10 were significantly higher than those in <10 patients (P<005). Mean serum AMH levels in patients with successful pregnancy were higher than those in patients with failed pregnancy (P<005). ConclusionThe serum AMH level is related to the ovarian reserve function, the number of follicles and the pregnancy rate after the operation of ovarian endometriosis cyst. It can be used as an important reference index for the evaluation of premature ovarian failure.

参考文献/References:

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更新日期/Last Update: 2018-08-25