[1]程建红*,白凤姬,王卫娟,等.预存式自体输血在产后出血高危因素产妇中的 应用观察[J].中国计划生育和妇产科,2018,(7):52-55.
　CHENG Jian-hong*,BAI Feng-ji,WANG Wei-juan,et al.Application of predeposit autologous blood transfusion in puerperas with high-risk of postpartum hemorrhage[J].Chinese Journal of Family Planning & Gynecotokology,2018,(7):52-55.
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预存式自体输血在产后出血高危因素产妇中的 应用观察
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2018年7期
页码:
52-55
栏目:
论著与临床
出版日期:
2018-07-25

文章信息/Info

Title:
Application of predeposit autologous blood transfusion in puerperas with high-risk of postpartum hemorrhage
作者:
程建红1*; 白凤姬1 ; 王卫娟1;  潘国艳1;  闫少菲2
1. 065700河北廊坊，廊坊市第四人民医院妇产科；2. 065700河北廊坊，霸州市第三医院急诊科
Author(s):
CHENG Jian-hong1*;  BAI Feng-ji1;  WANG Wei-juan1;  PAN Guo-yan1;  YAN Shao-fei2
1.Department of Obstetrics and Gynecology, the Fourth People’s Hospital of Langfang City,Langfang Hebei 065700,P.R.China; 2.Emergency Department, the Third Hospital of Bazhou City, Bazhou Hebei 065700, P.R.China
关键词:
预存式自体输血; 高危产妇; 产后出血
Keywords:
predeposit autologous blood transfusion;  high-risk puerperas;  postpartum hemorrhage
分类号:
R 714.46+1
摘要:
目的探讨预存式自体输血在产后出血高危因素产妇中的应用效果及安全性。方法选择2015年3月至2017年4月廊坊市第四人民医院50例存在产后出血高危因素的产妇为自体输血组，在分娩前3周开始采集自体血，对估计出血量较多者可在分娩前3～7 d进行第2次采血。同期未实施自体输血高危产妇 50例为对照组。观察自体血采集及回输过程中母胎变化情况以及产妇血压、心率、呼吸情况。对比分析采血前后、自血回输前后红细胞(red blood cell，RBC)、血红蛋白(hemoglobin，Hb)、血细胞比容(hematocrit，Hct)及血小板(platelets，Plt)等血常规相关指标变化情况。结果① 自体输血组产妇自体血采集及回输过程中未出现严重不良反应。胎心音采血前［(146±10)次/min］后［(143±9)次/min］比较,差异无统计学意义(P＞005)。新生儿Apgar评分为9～10 分。② 高危产妇自体血采集前后和自体血回输前后血压、心率、呼吸比较，差异均无统计学意义（P＞005），RBC、Hb、Hct、Plt等指标无显著变化（P＞005）。③ 两组出血例数、累计出血量、子宫切除例数比较，差异无统计学意义（P＞005）。自体输血组共回输自体血6 400 mL，异体输血量明显低于对照组（P＜005）。结论预存式自体输血操作简单、安全性好，对产后出血高危产妇及胎儿无明显不良影响，具有一定推广应用价值。
Abstract:
ObjectiveTo observe the effect and safety of predeposit autologous blood transfusion in puerperas with high-risk of postpartum hemorrhage.Methods50 cases of puerperas with high-risk of postpartum hemorrhage in Fourth People’s Hospital of Langfang City from March 2015 to April 2017 were selected as the autologous blood transfusion group，autologous blood was collected 3 weeks prior to delivery, and blood was collected for the second time on the estimated excessive bleeding 3 to 7 days prior to delivery. In the same period, 50 cases of puerperas with high-risk of postpartum hemorrhage without self-transfusion were included in the control group. Observed maternal and fetal changes and maternal blood pressure, heart rate, respiratory conditions in self blood collection and return process.The changes of red blood cell (RBC), hemoglobin (Hb), hematocrit (Hct) and platelets (Plt) were compared before and after blood collection and transfusion. Results ① No serious adverse reaction occurred in the process of blood collection and transfusion in the autologous blood transfusion group.Fetal heart sound was (146±10) times/min before blood collection, and (143±9) times/min after blood collection, there was no significant difference (P>005).The Apgar score of the newborn was 9~10 scores.② Blood pressure, heart rate, breathing before and after autologous blood collection ,transfusion had no significant changes (P>005). RBC, Hb, Hct, Plt and other indicators had no significant changes (P>005).③ Autologous blood 6 400 mL was transfused in autologous blood transfusion group.Hemorrhage cases, cumulative blood loss, hysterectomy cases in autologous blood transfusion group were not statistically different from control group, the allogeneic blood transfusion was significantly lower than control group (P<005).ConclusionPredeposit autologous blood transfusion is simple and safe, and has no obvious adverse influences on high-risk puerperas with postpartum hemorrhage and worthy of clinical popularization and application.

参考文献/References:

［1］黄晓宇，管菊艳，董亮，等．储存式自体输血在前置胎盘患者中应用的安全性分析 ［J］．临床血液学杂志，2014，27（12）：1014-1015． ［2］郑英，孔文兵，孙玉华，等．储存式自体输血在择期手术患者中的应用与血液保护 ［J］．中国输血杂志，2013，26（8）：690-691． ［3］黄颖，林甲进，裘晓乐．储存式自体采血对Rh(D)阴性孕妇妊娠结局影响 ［J］．北京医学，2013，35（11）：971, 974． ［4］林甲进，朱碎永．妊娠晚期贮存式自体输血对母婴预后的影响 ［J］．医学研究杂志，2013，42（2）：100-102． ［5］章林燕．妊娠晚期预存式自体输血在双胎孕妇中的应用 ［J］．中国妇幼保健，2013，28（20）：3383-3385． ［6］张丽娟，廖滔，林忠．两种自体输血方式在中央性前置胎盘孕妇中应用的安全性分析 ［J］．生殖医学杂志，2017，26（5）：447-451． ［7］胡小兵，肖素香，王伯亮．30例Rh D阴性患者术中自体血回输的效果分析 ［J］．重庆医学，2013，42（2）：191-192． ［8］王怡涵．预存式自体输血治疗Rh(D)阴性大出血孕妇的临床研究 ［J］．中国妇幼保健，2015，30（33）：5929-5930． ［9］林毅，张仕铜，严海雅，等．凶险性前置胎盘行剖宫产时两种自体血回输应用比较 ［J］．实用妇产科杂志，2016，32（1）：38-41．

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备注/Memo

备注/Memo:
廊坊市科学技术研究与发展计划项目（项目编号：2017013039）
更新日期/Last Update: 2018-07-25