[1]陈丽敏.垂体后叶素不同剂量及其注射方式对腹腔镜下 子宫肌瘤剔除术的临床疗效[J].中国计划生育和妇产科,2018,(8):90-93.
　CHEN Li-min.Observation on pituitrin and its different injection methods on the clinical effects of laparoscopic myomectomy[J].Chinese Journal of Family Planning & Gynecotokology,2018,(8):90-93.
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垂体后叶素不同剂量及其注射方式对腹腔镜下 子宫肌瘤剔除术的临床疗效
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2018年8期
页码:
90-93
栏目:
论著与临床
出版日期:
2018-08-25

文章信息/Info

Title:
Observation on pituitrin and its different injection methods on the clinical effects of laparoscopic myomectomy
作者:
陈丽敏
简阳市人民医院妇科
Author(s):
CHEN Li-min
Department of Gynecology，the People's Hospital of Jianyang City，Chengdu Sichuan 641400，P.R.China
关键词:
腹腔镜; 子宫肌瘤剔除术; 垂体后叶素分离法; 直接剥离法
Keywords:
laparoscopy; myomectomy; pituitrin separation; direct dissection
分类号:
R 711.74
摘要:
目的比较垂体后叶素不同剂量、不同注射方案对腹腔镜下子宫肌壁间肌瘤剔除术的临床疗效及对循环系统的影响。 方法选取2015～2016年在简阳市人民医院接受腹腔镜下子宫肌瘤剔除术的420例患者作为研究对象，按随机数字表法分为对照组与观察组，各210例，对照组采取直接剥离法，观察组采取垂体后叶素液体分离法；另观察组根据注射方式及剂量不同分为3个亚组，各70例，A亚组（6 U一次注射）、B亚组（6 U分两次注射）、C亚组（12 U一次注射）；比较两组的手术时间、术中出血量、用药前后血压变化、手术前后血红蛋白变化、术后肛门排气时间、术后抗生素使用时间、术后住院时间及并发症发生情况等指标。结果观察组术中出血量、手术时间及术后住院时间均显著少于对照组（P＜005）；观察组垂体后叶素注射后10 min收缩压显著上升，收缩压变化明显高于对照组（P＜005）；观察组术后血红蛋白下降值、抗生素使用时间均明显少于对照组（P＜005）；观察组各亚组间比较，B亚组术中出血量、术后血压波动情况及术后血红蛋白下降值方面均优于A亚组和C亚组，差异有统计学意义（P<005）。结论腹腔镜下行子宫肌瘤剔除术应用小剂量分次注射垂体后叶素液体分离法，能够显著减少术中出血，有效缩短手术时间、抗生素使用时间及住院时间，利于患者术后恢复，值得临床推广。
Abstract:
ObjectiveTo compare the clinical effects of different doses of pituitrin and different injection methods on laparoscopic myomectomy and its influence on circulatory system. MethodsFrom 2015 to 2016, 420 patients underwent laparoscopic myomectomy in the People's Hospital of Jianyang City were selected as the study subjects. They were randomly divided into control group and observation group,each with 210 cases. The control group was treated with direct stripping method and the observation group was treated with pituitrin liquid separation method. According to the observation group's injection method and measurement,they were divided into three subgroups: 70 cases, A subgroup (one injection fo 6 U), B subgroup (two injections of 6 U), and C subgroup (one injection of 12 U);The operation time, intraoperative blood loss,blood pressure changes before and after medication,hemoglobin changes before and after surgery,postoperative anal exhaust time,postoperative antibiotic use time,postoperative hospital stay and complications were compared between the two groups.ResultsThe intraoperative blood loss, the time of operation and the time of hospitalization were significantly lower in the observation group than in the control group(P<005).The systolic blood pressure of the observation group was significantly increased at 10 min after injection of pituitrin, and the systolic blood pressure was significantly higher than that of the control group (P<005).The decrease of hemoglobin and the time of antibiotic use in the observation group were significantly lower than those in the control group(P<005).The intraoperative blood loss, postoperative blood pressure fluctuation and postoperative hemoglobin decline in B subgroup were superior to subgroup A and C subgroup, the differences were statistically significant (P<005).ConclusionLaparoscopic myomectomy with low dose fractional injection of pituitrin liguid separation can be used to reduce the intraoperative bleeding, reduce the operation time, antibiotic use time and discharge time, which is beneficial to the postoperative recovery of patients. It is worthy of clinical promotion.

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更新日期/Last Update: 2018-08-25