[1]洪喜萍,奚杰*.孕中期超声检测子宫动脉血流联合平均动脉压预测妊娠期高血压疾病的价值研究[J].中国计划生育和妇产科,2018,(8):57-61.
 HONG Xi-ping,XI Jie*.The value of ultrasonographic detection of uterine arterial blood flow combined with mean arterial pressure in second trimester to predict hypertensive disorder complicating pregnancy[J].Chinese Journal of Family Planning & Gynecotokology,2018,(8):57-61.
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孕中期超声检测子宫动脉血流联合平均动脉压预测妊娠期高血压疾病的价值研究
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2018年8期
页码:
57-61
栏目:
论著与临床
出版日期:
2018-08-25

文章信息/Info

Title:
The value of ultrasonographic detection of uterine arterial blood flow combined with mean arterial pressure in second trimester to predict hypertensive disorder complicating pregnancy
作者:
洪喜萍奚杰*
上海市嘉定区妇幼保健院妇产科
Author(s):
HONG Xi-ping XI Jie*
Department of Gynecology and Obstetrics, Jiading Maternal and Child Health Hospital, Shanghai 201821,P.R.China
关键词:
妊娠期高血压疾病子宫动脉搏动指数子宫动脉阻力参数平均动脉压预测价值
Keywords:
hypertensive disorder complicating pregnancy uterine artery pulsatility index uterine artery resistance parameters mean arterial pressure predictive value
分类号:
R 445.1
摘要:
目的探讨孕中期超声检测子宫动脉搏动指数(uterine arterial pulsatility index,PI)、子宫动脉阻力参数(uterus artery resistance index,RI)联合平均动脉压(mean arterial pressure,MAP)预测妊娠期高血压疾病(hypertensive disorders complicating pregnancy,HDCP)的价值。方法选取2016年7月至2017年12月嘉定妇幼保健医院就诊的孕妇4 000例,随诊至妊娠终止,根据HDCP诊断标准,发生HDCP的397例为HDCP组,未发生HDCP的3 603例为正常妊娠组。比较两组孕妇孕16周时PI、RI及MAP情况,评估3项指标单独及联合监测时对HDCP的预测价值。结果与正常妊娠组相比,HDCP组RI、PI和MAP值均显著增加(P<005)。RI≥058为阳性时,200例发生HDCP,阳性预测值4415 %,敏感性5038 %,特异性9298 %,准确性8875 %。PI≥130为阳性时,227例发生HDCP,阳性预测值4719 %,敏感性5718 %,特异性9295 %,准确性8940 %。MAP≥85 mmHg为阳性时,315例发生HDCP,阳性预测值3860 %,敏感性7935 %,特异性8609 %,准确性8543 %。RI、PI、MAP平行联检时,353例发生HDCP,阳性预测值4021 %,敏感性8892 %,特异性8543 %,准确性8578 %。RI、PI、MAP系列联检时,196例发生HDCP,阳性预测值4769 %,敏感性4937 %,特异性9403 %,准确性8960 %。3项指标平行联检时的敏感性高于RI、PI、MAP单独检测(P<005);3项指标系列联检时的特异性、准确性和阳性预测值均高于RI、PI、MAP单独检测(P<005)。结论孕中期超声检测子宫动脉血流参数联合平均动脉压监测对HDCP的预测价值优于单独检测,对早期发现、早期预防、及时治疗HDCP具有积极的临床意义.
Abstract:
ObjectiveTo evaluate the value of detecting the uterine arterial pulsatility index(PI), uterine artery resistance index(RI) and mean arterial pressure(MAP) in the prediction of hypertensive disorder complicating pregnancy(HDCP) during the second trimester of pregnancy.MethodsFrom July 2016 to December 2017, 4 000 pregnant women at the Jiading Maternal and Child Health Hospital were selected and followed up until termination of pregnancy. According to the HDCP diagnostic criteria, HDCP occurred in 397 HDCP patients, and 3 603 without HDCP were in the normal pregnancy group. The PI, RI, and MAP levels at 16 weeks' gestation were compared between the two groups of pregnant women to evaluate the predictive value of the three indicators alone and in joint monitoring for HDCP. ResultsCompared with normal pregnancy group, RI, PI and MAP in HDCP group were significantly increased (P<005).When RI ≥ 058 was positive, HDCP was detected in 200 cases, with a positive predictive value of 4415 %, a sensitivity of 5038 %, a specificity of 9298 % and an accuracy of 8875 %.When PI ≥ 130 was positive, HDCP occurred in 227 patients with a positive predictive value of 4719 %, a sensitivity of 5718 %, a specificity of 9295 %, and an accuracy of 8940 %.When MAP≥85 mmHg was positive, HDCP was detected in 315 cases, the positive predictive value was 3860 %, the sensitivity was 7935 %, the specificity was 8609 % and the accuracy was 8543 %.HDCP was detected in 196 cases with RI, PI and MAP series. The positive predictive value was 4769 %, the sensitivity was 4937 %, the specificity was 9403 % and the accuracy was 8960 %.The sensitivities of the three indexes in parallel examination were higher than those of RI, PI and MAP alone(P<005);the specificity, accuracy and positive predictive value of the three indexes were higher than that of RI, PI and MAP alone (P<005).ConclusionThe predictive value of uterine artery blood flow parameters combined with mean arterial blood pressure monitoring during the second trimester is superior to that of single detection. It has positive clinical significance for early detection, early prevention, and timely treatment of HDCP.

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备注/Memo

备注/Memo:
上海市嘉定区妇幼保健院(课题编号:2015-KY-10)
更新日期/Last Update: 2018-08-25