[1]李国臻,段新崇*,杨志伟,等.冻融周期中D 5、D 5加D 6、D 6期囊胚移植妊娠结局比较[J].中国计划生育和妇产科,2019,(7):24-27.
　LI Guo-zhen,DUAN Xin-chong*,YANG Zhi-wei,et al.Comparative study of the clinical outcomes of D 5,D 5+D 6,D 6 periods frozen-thawed embryo transplantation[J].Chinese Journal of Family Planning & Gynecotokology,2019,(7):24-27.
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冻融周期中D 5、D 5加D 6、D 6期囊胚移植妊娠结局比较
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2019年7期
页码:
24-27
栏目:
论著与临床
出版日期:
2019-06-25

文章信息/Info

Title:
Comparative study of the clinical outcomes of D 5,D 5+D 6,D 6 periods frozen-thawed embryo transplantation
作者:
李国臻; 段新崇*; 杨志伟; 陶林林; 耿亚松; 郑波
邢台不孕不育专科医院/邢台生殖与遗传专科医院生殖实验室
Author(s):
LI Guo-zhen; DUAN Xin-chong*; YANG Zhi-wei; TAO Lin-lin; GENG Ya-song; ZHENG Bo
Reproductive Laboratory, Xingtai Infertility Specialist Hospital /Xingtai Reproductive and Genetic Specialist Hospital，Xingtai Hebei 054000，P.R.China
关键词:
冻融囊胚移植; 胚胎发育天数; D 5+D 6囊胚
Keywords:
freeze-thaw blastocyst transfer;  embryo development days;  D 5+D 6 blastocyst
分类号:
R 7137
摘要:
目的比较分析冻融囊胚移植 (frozen-thawed embryo transfer，FET) 周期移植第5 d（D 5）双囊胚、第5 d＋第6 d（D 5＋D 6）混合双囊胚、第6 d（D 6）双囊胚的临床妊娠结局。方法回顾性分析2014 年1月至2018 年6月在邢台不孕不育专科医院接受FET 且移植2枚囊胚的1 578个周期的临床结局，根据移植囊胚的发育天数分为3 组：D 5组为解冻第 5 d双囊胚移植组（821个周期）；D 5＋D 6组为解冻第5 d加第6 d各1枚囊胚移植组（226个周期）；D 6 组为解冻第6 d双囊胚移植组（531个周期）。结果3组患者平均年龄、不孕年限、内膜厚度、基础卵泡刺激素等基础数值比较，差异无统计学意义 (P>005)；D 5+D 6组的临床种植率（5774 %）、妊娠率（7655 %）高于D 5组（5188 %、6906 %）和D 6组（3700 %、5612 %）（P＜005）；D 5组高于D 6组（P＜005）。结论FET周期中移植D 5＋D 6囊胚比单纯移植D 5或D 6囊胚有更好的妊娠结局，D 5囊胚比D 6囊胚有更好的妊娠结局。
Abstract:
Objective To compare the difference of clinical pregnancy outcomes of frozen-thawed embryo transfer (FET) cycle transplantation of double day 5（D 5） blastocysts, mixed double day 5+day 6（D 5+D 6） blastocysts and double day 6（D 6） blastocysts. MethodsRetrospectively analyzed the clinical outcomes of 1 578 cycles of receiving FET and transplanting 2 blastocysts in Xingtai Infertility Specialist Hospital from January 2014 to June 2018, according to the development days of transplanted blastocysts, they were divided into 3 groups：the D 5 group， on the 5th thawed day double blastocysts transferred (821 cycles); the D 5+D 6 group， 2 blastocysts transferred on the 5th thawed day plus the 6th day (226 cycles); D 6 group，on the thawed 6th day double blastocysts transferred (531 cycles).ResultsThere were no significant differences in the mean age, infertility years, intimal thickness, and basic follicle stimulating hormone between the three groups (P>005). The clinical implantation rate (5774 %) and pregnancy rate (7655 %) in D 5+D 6 group were higher than those in D 5 group (5188 %, 6906 %) and D 6 group (3700 %, 5612 %) (P<005); D 5 group was higher than D 6 group (P<005).ConclusionTransplantation of D 5+D 6 blastocysts in the FET cycle has a better pregnancy outcome than transplantation of D 5 or D 6 blastocysts， D 5 blastocysts have better pregnancy outcomes than D 6 blastocysts.

参考文献/References:

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更新日期/Last Update: 2019-07-25