[1]曹鹏燕,王治鸿*.冻融胚胎移植中子宫内膜不同转化时间对妊娠 结局的影响[J].中国计划生育和妇产科,2019,(7):28-31.
 CAO Peng-yan,WANG Zhi-hong*.Effects of different endometrial transformation time on pregnancy outcomes in freeze-thaw embryo transfer[J].Chinese Journal of Family Planning & Gynecotokology,2019,(7):28-31.
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冻融胚胎移植中子宫内膜不同转化时间对妊娠 结局的影响
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2019年7期
页码:
28-31
栏目:
论著与临床
出版日期:
2019-06-25

文章信息/Info

Title:
Effects of different endometrial transformation time on pregnancy outcomes in freeze-thaw embryo transfer
作者:
曹鹏燕1王治鸿2*
1. 山西医科大学;2.山西医科大学第一医院生殖医学中心
Author(s):
CAO Peng-yan1WANG Zhi-hong2*
1. Shanxi Medical University; 2. Reproductive Medicine Center, First Hospital of Shanxi Medical University,Taiyuan Shanxi 030000,P.R.China
关键词:
孕酮胚胎移植子宫内膜容受性妊娠结局
Keywords:
progesteroneembryo transferendometrial receptivitypregnancy outcome
分类号:
R 713.7
摘要:
目的探讨冻融胚胎移植中不同内膜转化时间对妊娠结局的影响。方法回顾性分析2017年山西医科大学第一医院生殖医学中心采用激素替代周期准备子宫内膜进行冻融胚胎移植的895个周期的妊娠结局。根据孕酮转化子宫内膜时间的不同分为两组,A组:600个周期随机抽样300个周期,孕酮转化子宫内膜后3 d移植D 3胚胎;B组:295个周期,孕酮转化子宫内膜后4 d移植D 3胚胎。比较两组种植率、临床妊娠率、异位妊娠率、多胎妊娠率、早期流产率、活产率。结果两组患者的不孕原因、不孕类型、年龄、不孕年限、移植日子宫内膜厚度、体质量指数、解冻胚胎数、移植胚胎数、优质胚胎率、种植率、临床妊娠率、异位妊娠率、多胎妊娠率、早期流产率、活产率比较,差异均无统计学意义(P>005)。结论冻融胚胎移植中孕酮转化内膜后3 d、4 d移植胚胎均可获得满意的妊娠结局。
Abstract:
Objective To explore the effects of different endometrial transformation time on pregnancy outcomes in freeze-thaw embryo transfer. MethodsRetrospective analysis of the pregnant outcome of 895 frozen-thawed embryo transfer cycles using hormone replacement therapy endometrial preparation were studied retrospectively in Reproductive Center of the First Hospital of Shanxi Medical University in 2017. Divided into two groups according to the time of progesterone conversion endometrium:group A:300 cycles were randomly sampled in 600 cycles, and D 3 embryos were transplanted 3 days after endometrial progesterone preparation; group B:295 cycles, D 3 embryos were transplanted 4 days after endometrial progesterone preparation. The rate of implantation,clinical pregnancy rate,ectopic pregnancy rate,multiple pregnancy rate, first trimester abortion rate and live birth rate were compared between the two groups.ResultsThere were no significant differences in infertility causes, infertility types, age, infertility years, endometrial thickness on transplant day, body mass index, number of thawed embryos, number of transplanted embryos, high quality embryos ,implantation rate, clinical pregnancy rate, ectopic pregnancy rate, multiple pregnancy rate, early abortion rate, and live birth rate between the two groups (P>005). ConclusionSatisfactory pregnancy outcomes were obtained after 3 d, 4 d transformation of progesterone into endometrium in freeze-thaw embryo transfer.

参考文献/References:

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备注/Memo

备注/Memo:
山西省自然科学基金(项目编号:201701D121174)
更新日期/Last Update: 2019-07-25