[1]马洁,郭敏,王文玲,等.中孕期孕妇血清学产前筛查联合无创产前DNA检测在胎儿染色体非整倍体疾病筛查中的价值分析[J].中国计划生育和妇产科,2019,(11):33-37.
　MA Jie,GUO Min,WANG Wen-ling,et al.Value analysis of serological prenatal screening combined with non-invasive prenatal DNA testing screening for fetal chromosome aneuploidy disease in pregnant women in the second trimester[J].Chinese Journal of Family Planning & Gynecotokology,2019,(11):33-37.
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中孕期孕妇血清学产前筛查联合无创产前DNA检测在胎儿染色体非整倍体疾病筛查中的价值分析
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2019年11期
页码:
33-37
栏目:
论著与临床
出版日期:
2019-11-25

文章信息/Info

Title:
Value analysis of serological prenatal screening combined with non-invasive prenatal DNA testing screening for fetal chromosome aneuploidy disease in pregnant women in the second trimester
作者:
马洁; 郭敏; 王文玲; 王慧琴; 张彩荣; 木合塔尔江·木沙; 朱开春*
新疆维吾尔自治区人民医院妇产科研究室
Author(s):
MA Jie;  GUO Min;  WANG Wen-ling;  WANG Hui-qin;  ZHANG Cai-rong;  Muhtar·Musha; ZHU Kai-chun*
Department of Obstetrics and Gynecology, Xinjiang Uygur Autonomous Region People's Hospital, Urumqi Xinjiang 830001,P.R. China
关键词:
非整倍体; 血清学产前筛查; 无创产前DNA检测; 联合筛查
Keywords:
aneuploidy;  serological prenatal screening;  non-invasive prenatal DNA testing;  combined screening
分类号:
R 7155
摘要:
目的探讨中孕期孕妇血清学产前筛查联合无创产前DNA检测（noninvasive prenatal testing,NIPT）在筛查胎儿染色体非整倍体疾病中的临床应用价值。方法对2017年新疆维吾尔自治区人民医院妇产科2 068例孕妇行三联中孕期母血清学产前筛查，对筛查结果为21-三体和18-三体高风险的孕妇，则建议行羊膜腔穿刺或者NIPT，并告知NIPT的局限性和羊膜腔穿刺的有创性，由孕妇自行选择。建议风险值≥1/1 000、年龄≥35岁及单项血清中位数倍数值异常的孕妇行NIPT检测，若行NIPT则以NI
Abstract:
ObjectiveTo discuss value of serological prenatal screening combined with non-invasive prenatal DNA testing (NIPT) screening for fetal chromosome aneuploidy disease in pregnant women in the second trimester.MethodsIn 2017, 2 068 pregnant women in the Dep

参考文献/References:

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更新日期/Last Update: 2019-11-25