[1]王红琳*,吴正红,陈亚萍.重度子痫前期患者血浆中环状 RNA 差异表达分析[J].中国计划生育和妇产科,2019,(8):57-61.
　WANG Hong-lin*,WU Zheng-hong,CHEN Ya-ping.Analysis of differential expression of circular RNA in plasma of patients with severe preeclapsia[J].Chinese Journal of Family Planning & Gynecotokology,2019,(8):57-61.
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重度子痫前期患者血浆中环状 RNA 差异表达分析
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2019年8期
页码:
57-61
栏目:
论著与临床
出版日期:
2019-08-25

文章信息/Info

Title:
Analysis of differential expression of circular RNA in plasma of patients with severe preeclapsia
作者:
王红琳*; 吴正红; 陈亚萍
复旦大学附属上海市第五人民医院妇产科
Author(s):
WANG Hong-lin*; WU Zheng-hong; CHEN Ya-ping
Department of Obstetrics and Gynecology, The Fifth People's Hospital of Shanghai,Fudan University, Shanghai 200240, P.R.China
关键词:
妊娠期高血压疾病; 环状 RNA ; 早期诊断; 标志物
Keywords:
gestational hypertension; circular RNA; early diagnosis;  markers
分类号:
R 714.2
摘要:
目的分析重度子痫前期患者血浆中环状 RNA 表达特征，为进一步研究差异表达的环状 RNA 并筛选重度子痫前期患者早期诊断标志物打下基础。方法选取2016年6月至2018年6月在上海市第五人民医院妇产科分娩的重度子痫前期孕妇40例为观察组，40例正常孕妇为对照组，每个研究对象抽取10 mL全血并制备血浆。随机选取5例重度子痫前期患者及正常孕妇的样本，采用Trizol法提取总RNA。将标记的环状 RNA 与Arraystar Human 环状 RNA芯片杂交。对所获得的数据进行分析，筛选出观察组与对照组之间存
Abstract:
ObjectiveTo analyze the expression of circular RNA in plasma of patients with severe preeclapsia (SPE), and to lay the foundation for further study of differentially expressed circular RNA and screening for early diagnosis markers of SPE patients. Methods

参考文献/References:

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备注/Memo

备注/Memo:
上海市闵行区自然科学基金（项目编号:2016MHZ23）;上海市闵行区医学特色专科（项目）建设（项目编号：2017MWTZ05）
更新日期/Last Update: 2019-08-25