[1]毛亚静*,陆勤,奚杰,等.内皮细胞微粒与CD 8+ CD 25+ FoxP 3+ 调节 T细胞对子痫前期发生发展的作用探究[J].中国计划生育和妇产科,2019,(12):57-60.
　MAO Ya-jing*,LU Qin,XI Jie,et al.Effect of endothelial cell microparticles and CD8+CD25+FoxP3+ regulatory T cells on the development of preeclampsia[J].Chinese Journal of Family Planning & Gynecotokology,2019,(12):57-60.
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内皮细胞微粒与CD 8+ CD 25+ FoxP 3+ 调节 T细胞对子痫前期发生发展的作用探究
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2019年12期
页码:
57-60
栏目:
论著与临床
出版日期:
2019-12-25

文章信息/Info

Title:
Effect of endothelial cell microparticles and CD8+CD25+FoxP3+ regulatory T cells on the development of preeclampsia
作者:
毛亚静1*; 陆勤1; 奚杰1; 王磊2
1.201821上海，嘉定区妇幼保健院妇产科；2. 200092上海，上海交通大学附属新华医院妇产科
Author(s):
MAO Ya-jing1*; LU Qin1; XI Jie1; WANG Lei2
1. Department of Obstetrics and Gynecology, Maternal and Child Health Hospital of Jiading District, Shanghai 201821, P.R.China; 2. Department of Obstetrics and Gynecology, Xinhua Hospital Affiliated of Shanghai Jiaotong University, Shanghai 200092, P.R.Ch
关键词:
内皮细胞微粒; 调节T细胞; 子痫前期; 细胞因子
Keywords:
endothelial cell microsomes;  regulatory T cells;  preeclampsia;  cytokines
分类号:
R 714.24+4
摘要:
目的通过探讨子痫前期患者外周血内皮细胞微粒（endothelial microparticles，EMPs）与CD 8+ CD 25+ FoxP 3+ 调节T细胞（regulatory T cell，Treg）之间关系，阐明EMPs对Treg功能影响及其在子痫前期发病过程中的机制。方法选取2017年6月至2018年5月在上海市嘉定区妇幼保健院行产检的子痫前期孕妇60例为研究组，其中38例非重度子痫前期患者为A组，22例重度子痫前期患者为B组；同时随机选取60例健康孕妇为对照组。收集所有孕妇外周血，应用流式
Abstract:
ObjectiveTo investigate the relationship between endothelial microparticles （EMPs） and CD 8+CD 25+FoxP 3+ regulatory T cells（Treg） in patients with preeclampsia, and to elucidate the effects of EMPs on T regulatory cell function and its mechanism in the p

参考文献/References:

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备注/Memo

备注/Memo:
上海市嘉定区医学重点专科（产科）（项目编号：JDYXZDZK-8）
更新日期/Last Update: 2019-12-25