[1]陈震宇,孙静莉*,陈晓明,等.剖宫产术后再次妊娠阴道分娩的妊娠结局[J].中国计划生育和妇产科,2020,(5):58-63,68.
 CHEN Zhenyu,SUN Jingli*,CHEN Xiaoming,et al.Pregnant outcome of vaginal birth after cesarean[J].Chinese Journal of Family Planning & Gynecotokology,2020,(5):58-63,68.
点击复制

剖宫产术后再次妊娠阴道分娩的妊娠结局
分享到:

《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2020年5期
页码:
58-63,68
栏目:
论著与临床
出版日期:
2020-05-25

文章信息/Info

Title:
Pregnant outcome of vaginal birth after cesarean
作者:
陈震宇孙静莉*陈晓明仲莞金珈汐
北部战区总医院和平院区妇产科
Author(s):
CHEN Zhenyu SUN Jingli* CHEN Xiaoming ZHONG Wan JIN Jiaxi
Department of Obstetrics and Gynecology, General Hospital of Northern Theatre Command (Heping Campus), Shenyang Liaoning 110003, P.R.China
关键词:
剖宫产后阴道分娩妊娠结局产程
Keywords:
vaginal birth after cesarean pregnancy outcome labor
分类号:
R 7144
摘要:
目的分析剖宫产术后阴道分娩(vaginal birth after cesarean, VBAC)产妇的产时特点及妊娠结局。方法选取2015年1月至2019年6月在北部战区总医院和平院区VBAC的122例产妇为研究对象(VBAC组),按1∶2配对病例对照设计,选择与VBAC产妇同时期分娩的重复性剖宫产(elective repeat cesarean section, ERCS)产妇244例(ERCS组)及经阴道分娩的初产妇244例(对照组),比较3组产妇的母婴结局,分析VBAC组的产时特点。结果① ERCS组年龄最大、孕次最多,对照组年龄最小、孕次最少;对照组受教育程度高于其他两组;ERCS组孕前体质量指数(body mass index, BMI)及分娩前BMI高于其他两组;VBAC组孕期增重低于其他两组,入院时宫颈Bishop评分最高,差异均有统计学意义(P<005)。② VBAC组分娩孕周(3847±182)周,低于对照组(P<005);VBAC组早产发生率最高、新生儿体重最低、巨大儿发生率最低(P<005);VBAC组产后出血量最多,对照组次之,ERCS组最少(P<005),VBAC组及对照组产后出血发生率高于ERCS组(P<005);VBAC组、对照组住院天数和住院费用均少于ERCS组(P<005);3组新生儿Apgar评分、转入NICU率、输血率、产褥病率比较,差异均无统计学意义(P>005); 3组中均无产妇及新生儿死亡。③ VABC组中自然临产率、阴道助产率、会阴侧切率高于对照组,引产率、分娩镇痛率、产程中应用缩宫素比例低于对照组,第一、二产程及总产程时间短于对照组,差异均有统计学意义(P<005)。结论控制体重,降低新生儿出生体重,更好地理解剖宫产术后阴道试产(trial of labor after cesarean delivery, TOLAC)产程特点,加强监测,有助于降低TOALC的风险,提高VBAC成功率,改善妊娠结局。
Abstract:
Objective To analyze the labor characteristics and pregnant outcome of vaginal birth after cesarean (VBAC) . Methods122 cases with VBAC in General Hospital of Northern Theatre Command (Heping Campus) from January 2015 to June 2019 were studied and set as VBAC group. In a 1∶2 matched casecontrol study, 244 cases of elective repeat cesarean section (ERCS group) and 244 primiparas of vaginal delivery (control group) who delivered during the same time were selected. The maternal and infant outcomes of the three groups of women were compared and the labor characteristics of the VBAC group were analyzed. Results① The ERCS group was the oldest and had the most pregnany times, the control group was the youngest and the pregnancy times was the least; the control group was more educated than the other two groups; the body mass index (BMI) before pregnancy and BMI before delivery were higher in the ERCS group than the other two groups. The VBAC group had lower weight gain during pregnancy than the other two groups. The cervical Bishop score was the highest at admission in the VBAC group,and the differences were statistically significant (P<005). ② The gestational weeks of the VBAC group [(38.47±1.82) weeks] was smaller than the control group (P<005). The incidence of preterm birth was the highest in the VBAC group, the lowest in the newborn weight and the incidence of macrosomia (P<005). The VBAC group had the highest postpartum hemorrhage, followed by the control group, and the ERCS group had the lowest postpartum hemorrhage (P<005). The incidence of postpartum hemorrhage in VBAC group and control group was higher than that in ERCS group (P<005). The hospitalization days and hospitalization expenses of VBAC group and control group were lower than those of ERCS group (P<005). There were no significant differences in Apgar score, NICU rate, blood transfusion rate and puerperal rate between the three groups (P>005). There were no maternal and neonatal deaths in the three groups.③ Spontaneous labor rate, operative vaginal delivery rate and episiotomy rate were higher in VBAC group than those in control group ,the rate of inducing labor, requiring spinal analgesia and using oxytocin during labor were lower in VBAC group than those in control group, the duration of the first stage, second stage and total labor stage in VBAC group were shorter than those in control group,the differences were statistically significant (P<005). ConclusionWeight control, reducing birth weight, better understanding of the characteristics of TOLAC labor, and strengthen monitoring will help to reduce the risk of TOLAC, increase the success of VBAC and improve pregnant outcomes.

参考文献/References:

[1]侯磊,李光辉,邹丽颖,等.全国剖宫产率及剖宫产指征构成比调查的多中心研究 [J].中华妇产科杂志,2014,49(10):728735. [2]Bulletin A P. 115:Vaginal birth after pervious cesarean delivery[J]. Obstet Gynecol, 2010, 116(2 Pt 1): 450463. [3]Hauk L.Planning for labor and vaginal birth after cesarean delivery: guidelines from the AAFP [J]. Am Fam Physician, 2015, 91(3): 197198. [4]Obstetricians SO, Canada GO. SOGC clinical practice guidelines.Guidelines for vaginal birth after previous cesarean birth.Number 155(Replaces guideline Number 147),February 2005[J]. Int J Gynaecol Obstet, 2005, 89(3): 319331. [5]Royal College of Obstetricians and Gynecologists.Birth after previous cesarean birth. In GreenTop guideline[M]. London: RCOG, 2007: 117. [6]中华医学会妇产科学分会产科学组.剖宫产术后再次妊娠阴道分娩管理的专家共识(2016)[J].中华妇产科杂志,2016,51(8):561564. [7]刘兴会,漆洪波.难产 [M].北京:人民卫生出版社,2015:151152. [8] WHO. WHO recommendations for the prevention and treatment of postpartum haemorrhage [G]. Geneva: World Health Organization, 2012. [9]谢幸,孔北华,段涛.妇产科学 [M].第9版.北京:人民卫生出版社,2018:219. [10]ZHANG Jun, Troendle J, Reddy UM, et al. Contemporary cesarean delivery practice in the United States [J]. Am J Obstet Gynecol, 2010, 203(4):326 e 1326 e 10. [11]屈在卿,马润玫,肖虹,等.剖宫产术后再次妊娠阴道试产孕妇的妊娠结局分析 [J].中华妇产科杂志,2016,51(10):748753. [12]倪晓田,单震丽,阮昇明,等.规范化剖宫产后阴道试产478例临床分析 [J].现代妇产科进展,2018,27(2):115117, 121. [13]伍绍文,鲁艺斐,赵海平,等.中国部分地区剖宫产后阴道分娩的影响因素研究 [J].中国计划生育学杂志,2016,24(11):734738. [14]Groves P, Neveu J, Cook C, et al. Are there differences between women who choose elective repeat caesarean versus trial of Labour in St.john's,NL?[J]. J Obstet Gynaecol Can, 2018, 40(7): 903909. [15]Li W H, Yang M J, Wang P H, et al. Vaginal birth after cesarean section: 10 years of experience in a tertiary medical center in Taiwan [J]. Taiwan J Obstet Gynecol, 2016, 55(3): 394398. [16]Mirteymouri M, Ayati S, Pourali L, et al. Evaluation of MaternalNeonatal outcomes in vaginal birth after cesarean delivery referred to maternity of academic hospitals [J]. J Family Reprod Health, 2016, 10(4): 206210. [17]伍绍文,何电,张为远.产时干预对剖宫产术后阴道分娩母婴结局的影响 [J].中华医学杂志,2017,97(7):512516. [18]Holm C, LanghoffRoos J, Petersen KB, et al. Severe postpartum haemorrhage and mode of delivery:a retrospective cohort study [J]. BJOG, 2012, 119(5): 596604. [19]仲莞,陈震宇,金珈汐.438例产后出血相关危险因素的临床分析 [J].中国计划生育和妇产科,2019,11(2):5054. [20]屈在卿,杨明辉,杜明钰,等.高龄孕产妇剖宫产术后再次妊娠阴道分娩的妊娠结局分析 [J].中华妇产科杂志,2017,52(8):521525. [21]Kaplanoglu M, Bulbul M, Kaplanoglu DA. Effect of multiple repeat cesarean sections on maternal morbidity: data from southeast Turkey [J]. Medical Science Monitor, 2015, 21(21):14471453. [22]Kruit H, Wilkman H, Tekay A, et al. Induction of labor by Foley catheter compared with spontaneous onset of labor after previous cesarean section: a cohort study[J]. Journal of Perinatology, 2017, 37(7): 787792. [23]Radan A P, AmylidiMohr S, Mosimann B, et al. Safety and effectiveness of labour induction after caesarean section using balloon catheter or oxytocin[J]. Swiss Med Wkly,2017, 147(11): w 14532. [24]Atia H, Ellaithy M, Altraigey A, et al. Mechanical induction of labor and ecbolicless vaginal birth after cesarean section: A cohort study [J]. Taiwan J Obstet Gynecol, 2018, 57(3): 421426. [25]Landon M B, Hauth J C, Leveno K J, et al. Maternal and perinatal outcomes associated with a trial of labor after prior cesarean delivery[J]. N Engl J Med, 2004, 351(25): 25812589. [26]LydonRochelle M, Holt VL, Easterling TR, et al. Risk of uterine rupture during labor among women with a prior cesarean delivery [J]. N Engl J Med, 2001, 345(1): 38. [27]Ashwal E, Hiersch L, Melamed N, et al. Pregnancy outcome after induction of labor in women with previous cesarean section [J]. Journal of MaternalFetal & Neonatal Medicine, 2015, 28(4): 386391. [28]王静,李菊,蔺莉,等.椎管内分娩镇痛在剖宫产术后再次妊娠阴道分娩中的应用 [J].中国微创外科杂志,2018,18(2):127129, 133. [29]Inbar R, Mazaaki S, Kalter A, et al. Trial of Labour after caesarean (TOLAC) is associated with increased risk for instrumental delivery [J]. J Obstet Gynaecol (Lahore), 2017, 37(1): 4447. [30]Grantz K L, GonzalezQuintero V, Troendle J, et al. Labor patterns in women attempting vaginal birth after cesarean with normal neonatal outcomes [J]. Am J Obstet Gynecol, 2015, 213(2): 226.e 1226.e 6. [31]Sondgeroth KE, Stout MJ, Graseck AS, et al. Progress of induced labor in trial of labor after cesarean delivery [J]. Am J Obstet Gynecol, 2015, 213(3): 420 e 1420 e 5. [32]Hehir MP, Rouse DJ, Miller RS, et al. Secondstage duration and outcomes among women who labored after a prior cesarean delivery [J]. Obstet Gynecol, 2018, 131(3): 514522. [33]VachonMarceau C, Demers S, Goyet MA, et al. Labor dystocia and the risk of uterine rupture in women with prior cesarean [J]. Am J Perinatol, 2016, 33(6): 577583. [34]AnimSomuah M, Smyth RM, Jones L. Epidural versus nonepidural or no analgesia in Labour [J]. Cochrane Database Syst Rev, 2011, 7(12): CD 000331.

相似文献/References:

[1]廖治,杨业洲.多发性硬化和妊娠[J].中国计划生育和妇产科,2009,(05):0.
[2]陆显义,王昊珏,周冠琼,等.先兆流产380例保胎治疗后继续妊娠结局分析[J].中国计划生育和妇产科,2009,(06):0.
[3]谭欣,朱明辉,贺贞,等.胚胎移植后14~16日血清β-HCG值与早期妊娠结局的关系[J].中国计划生育和妇产科,2010,(02):0.
 TAN Xin,ZHU Ming-hui,HE Zhen,et al.[J].Chinese Journal of Family Planning & Gynecotokology,2010,(5):0.
[4]黄卡立,檀大羡.3种黄体支持方法在体外受精-胚胎移植术后对妊娠结局的影响[J].中国计划生育和妇产科,2010,(03):0.
 HUANG Ka-Li,TAN Da-xian.[J].Chinese Journal of Family Planning & Gynecotokology,2010,(5):0.
[5]冯思伟,邹翠兰.胎盘早剥44例临床分析及妊娠结局[J].中国计划生育和妇产科,2010,(04):0.
[6]罗海全,李明,刘兴会,等.宫颈病变锥形切除术后妊娠不良结局相关因素分析[J].中国计划生育和妇产科,2010,(05):0.
 LUO Hai-quan,LI Ming,LIU Xing-hui ..[J].Chinese Journal of Family Planning & Gynecotokology,2010,(5):0.
[7]岳军,谢兰,陈廉,等.妊娠合并心脏病伴肺动脉高压43例临床分析[J].中国计划生育和妇产科,2011,(04):0.
 YUE Jun,XIE Lan,CHEN Lian,et al.[J].Chinese Journal of Family Planning & Gynecotokology,2011,(5):0.
[8]谭志娥.60例中期妊娠胎盘前置状态的临床观察[J].中国计划生育和妇产科,2011,(05):0.
 TAN Zhi-e.[J].Chinese Journal of Family Planning & Gynecotokology,2011,(5):0.
[9]潘玥,刘巧,朱绍密,等.妊娠期糖尿病胰岛素治疗的临床分析[J].中国计划生育和妇产科,2011,(06):0.
 PAN Yue,LIU Qiao,ZHU Shao-mi.[J].Chinese Journal of Family Planning & Gynecotokology,2011,(5):0.
[10]刘丽,胥光热.先天性心脏病术后对妊娠结局的影响[J].中国计划生育和妇产科,2011,(06):0.
 LIU Li,XU Guang-re ..[J].Chinese Journal of Family Planning & Gynecotokology,2011,(5):0.

备注/Memo

备注/Memo:
辽宁省自然科学基金指导计划(项目编号:20180551133)
更新日期/Last Update: 2020-05-25