[1]黎天皇*,李翠,孙乐标,等.妊娠合并支气管哮喘急性发作的危险因素分析[J].中国计划生育和妇产科,2020,(6):87-91.
　LI Tianhuang*,LI Cui,SUN Yuebiao,et al.Analysis of risk factors for acute exacerbation of bronchial asthma during pregnancy[J].Chinese Journal of Family Planning & Gynecotokology,2020,(6):87-91.
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妊娠合并支气管哮喘急性发作的危险因素分析
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2020年6期
页码:
87-91
栏目:
论著与临床
出版日期:
2020-06-25

文章信息/Info

Title:
Analysis of risk factors for acute exacerbation of bronchial asthma during pregnancy
作者:
黎天皇1*; 李翠1; 孙乐标1; 吴勤练2
琼海市人民医院,1.急诊科；2产科
Author(s):
LI Tianhuang1*; LI Cui1; SUN Yuebiao1; WU Qinlian2
1.Department of Emergency;2.Department of Obstetrics，Qionghai People's Hospital,Qionghai Hainan 571400,P.R.China
关键词:
妊娠; 支气管哮喘; 急性发作; 危险因素
Keywords:
pregnancy;  bronchial asthma;  acute attack;  risk factors
分类号:
R 714253
摘要:
目的探讨妊娠合并支气管哮喘急性发作的危险因素。方法回顾性分析2017年5月至2019年5月因妊娠合并支气管哮喘到琼海市人民医院治疗的128例患者的临床资料，根据支气管哮喘诊断标准分为发作组与未发作组，采用多因素Logistic回归分析妊娠合并支气管哮喘急性发作的影响因素。结果128例患者中发作56例（4375 %）。Logistic回归分析显示孕周≥14周，合并感染、不使用哮喘控制药物、焦虑、抑郁、维生素D＜2524 ng/mL、血清 IgE＞11258 IU/mL、白介素17(IL17)＞8239 ng/L是妊娠合并支气管哮喘急性发作的独立危险因素，差异有统计学意义（P＜005）。结论孕周≥14周，合并感染、不使用哮喘控制药物、焦虑、抑郁、维生素D＜2524 ng/mL、血清 IgE＞11258 IU/mL、IL17＞8239 ng/L是妊娠合并支气管哮喘急性发作的独立危险因素，对于这类患者临床上应给予重视。
Abstract:
ObjectiveTo explore the risk factors of acute exacerbation of bronchial asthma during pregnancy. MethodsThe clinical data of 128 patients who came to Qionghai People's Hospital from May 2017 to May 2019 due to pregnancy combined with bronchial asthma were analyzed retrospectively. According to the diagnostic criteria of bronchial asthma, they were divided into attack group and non-attack group. The influencing factors of pregnancy combined with acute attack of bronchial asthma were analyzed by multivariate logistic regression.ResultsAmong 128 patients, 56 (4375 %) had attacks. Logistic regression analysis showed that gestational weeks≥14 weeks, with infection, without asthma control drugs, anxiety, depression, vitamin D＜2524 ng/mL, serum IgE＞11258 IU/mL, IL17＞8239 ng/L were independent risk factors for acute attacks of gestational asthma (P＜005）.ConclusionThe gestational weeks≥14 weeks, infection, non use of asthma control drugs, anxiety, depression, vitamin D＜2524 ng/mL, serum IgE＞11258 IU/mL, IL17＞8239 ng/L are the independent risk factors for the acute attack of asthma in pregnancy. We should pay attention to these patients in clinic.

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更新日期/Last Update: 2020-06-25