[1]林华兰*,蓝柳冰,钟静.早发重度子痫前期患者24 小时尿蛋白定量与 妊娠结局的相关性[J].中国计划生育和妇产科,2016,(6):14- 16,20.
　LIN Hua-lan*,LAN Liu-bing,ZHONG Jing.Correlation between 24 h urinary protein quantitation level and pregnancy outcome in patients with severe early onset preeclampsia[J].Chinese Journal of Family Planning & Gynecotokology,2016,(6):14- 16,20.
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早发重度子痫前期患者24 小时尿蛋白定量与 妊娠结局的相关性
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2016年6期
页码:
14- 16,20
栏目:
论著与临床
出版日期:
2016-06-25

文章信息/Info

Title:
Correlation between 24 h urinary protein quantitation level and pregnancy outcome in patients with severe early onset preeclampsia
作者:
林华兰*; 蓝柳冰; 钟静
梅州市人民医院产科
Author(s):
LIN Hua-lan*;  LAN Liu-bing;  ZHONG Jing
Department of Obstetrics, People's Hospital of Meizhou City,Meizhou Guangdong 514031，P.R.China
关键词:
重度子痫前期; 24 h尿蛋白定量; 期待治疗; 妊娠结局
Keywords:
severe preeclampsia;  24 h urinary protein quantitation;  expectant treatment;  pregnancy outcome
分类号:
R 71424+3
摘要:
目的探讨早发重度子痫前期（severe preeclampsia，SPE）患者24 h尿蛋白定量与妊娠结局的关系。方法将2010年1月至2015年1月于广东省梅州市人民医院住院分娩的126例早发SPE患者按照24 h尿蛋白定量水平分为A组（≥5g）和B组（＜5g），两组均给予期待治疗，比较两组妊娠结局和母婴并发症。结果两组产妇主要并发症为胎盘早剥、溶血、肝酶升高及血小板减少（hemolysis elevateod liver enzymes and low platelets count syndrome，HELLP）综合征、子痫、重度胎儿生长受限、胸腹水、低蛋白血症，组间比较差异无统计学意义（P＞005），两组期待治疗时间和剖宫产率差异无统计学意义（P＞005）；A组新生儿入住NICU率、呼吸窘迫综合征发生率高于B组（P＜005），两组新生儿出生时孕周、体重、Apgar评分及颅内出血率、支气管肺发育不良率、围生儿死亡率差异均无统计学意义（P＞005）。结论早发型SPE患者不应将24 h尿蛋白定量作为判断病情和终止妊娠的单一指标，要结合孕周、临床表现、胎儿成熟度等综合判断，尽量延长孕周以改善新生儿的预后。
Abstract:
Objective To investigate the relationship between 24h urinary protein quantitation level and pregnancy outcome in patients with early onset of severe preeclampsia (SPE). MethodsAccordoring to the 24h urine protein quantitation level, 126 patients with early-onset SPE hospitalized in People's Hospital of Meizhou City from January 2010 to January 2015 were divided into group A (≥5g) and group B (＜5g). And patients of two groups were given expectant treatment, pregnancy outcomes and complications of mother and infant were compared. ResultsThere was no significant difference in time of expectant treatment between the two groups (P＞005), The main complications of puerperae were placental abruption, HELLP syndrome, eclampsia, severe fetal growth restriction, hydrothorax and ascite, hypoalbuminemia, and there were no significant differences between the two groups（P＞005），and there were no significant differences in the expectant treatment time and cesarean section rate(P＞005). Check in NICU rate, incidence of respiratory distress syndrome of the group A were higher than those of the group B（P＜005）. Gestational weeks, weight, and Apgar score at birth and intracranial hemorrhage rate, failure rate of bronchial lung development,the perinatal death rate of two groups had no significant difference(P>005). Conclusion24 h urine protein quantitation level should not be used as a single indicator to determine the severity and termination of pregnancy in patients with early onset SPE, so as to improve the prognosis of newborns， gestational age, clinical manifestation, fetal maturity and so on should be considered.

参考文献/References:

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更新日期/Last Update: 1900-01-01