[1]马骄,巨容*,胡旭红,等.新生儿眼底出血的危险因素分析[J].中国计划生育和妇产科,2016,(12):62-65.
　MA Jiao,JU Rong*,HU Xu-hong,et al.Risk factors of retinal hemorrhage in newborns[J].Chinese Journal of Family Planning & Gynecotokology,2016,(12):62-65.
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新生儿眼底出血的危险因素分析
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2016年12期
页码:
62-65
栏目:
论著与临床
出版日期:
2016-12-30

文章信息/Info

Title:
Risk factors of retinal hemorrhage in newborns
作者:
马骄; 巨容*;  胡旭红; 刘阳; 杜逸亭
成都市妇女儿童中心医院新生儿科
Author(s):
MA Jiao;  JU Rong*;  HU Xu-hong;  LIU Yang;  DU Yi-ting
Department of neonatology, Chengdu Women’s and Children’s Central Hospital, Chengdu Sichuan 610091,P.R.China
关键词:
新生儿; 眼底出血; 产妇血小板减少症; 顺产; 窒息
Keywords:
newborn infant;  retinal hemorrhage;  maternal thrombocytopenia; vaginal delivery; suffocation
分类号:
R 272.1
摘要:
目的探讨新生儿眼底出血（retinal hemorrhage，RH)的相关危险因素。方法选择2014年3月至2015年2月于成都市妇女儿童中心医院新生儿科应用RetcamⅢ视网膜眼底成像系统完成眼底检查的1 643例住院患儿，首次检查时间为其出生后1周内。收集受检患儿及其母亲的相关资料，对产妇年龄、妊娠期合并症（妊娠期高血压疾病、妊娠期糖尿病、胆汁淤积症、血小板减少症）、患儿胎龄、多胎、生产方式、新生儿窒息、头颅血肿等因素进行单因素方差分析，对P<005的临床因素行多因素Logistic回归分析。结果1 643例新生儿中发生RH者251例，Ⅰ~Ⅱ级出血159例，Ⅲ~Ⅳ级出血92例。多因素回归分析提示产妇血小板减少症、顺产、新生儿窒息为RH的危险因素，同时产妇血小板减少症、新生儿窒息与严重RH的发生相关（P<005），但窒息程度与RH程度无明确相关性（P＞005）。结论产妇血小板减少症为新生儿RH的危险因素且与严重RH发生相关。顺产、窒息亦为新生儿RH的危险因素。
Abstract:
ObjectiveTo explore the risk factors of retinal hemorrhage (RH) of newborns. Methods1 643 infants hospitalized in Chengdu Women’s and Children’s Central Hospital were enrolled in this study from March 2014 to February 2015. Eye examinations with RetCamⅢ were performed within 1 week of birth. Related information of newborns and their mothers were collected. One-way ANOVA was taken to analyze the factors, including maternal age, pregnancy complications (gestational hypertension, gestational diabetes, pregnancy cholestasis, thrombocytopenia), gestational age, multifetation, mode of delivery, suffocation, cranial hematoma, and then the clinical factors (P<005) were analyzed by multivariate logistic regression analysis. ResultsRH was found in 251 infants out of 1 643 cases. 159 infants were Ⅰ~Ⅱdegree retinal hemorrhage, while the other 92 cases were Ⅲ~Ⅳdegree retinal hemorrhage. Multivariate logistic regression analysis showed that maternal thrombocytopenia，vaginal delivery and suffocation were the risk factors of RH, meanwhile maternal thrombocytopenia and suffocation were associated with the presence of severe RH (P<005). There was no statistical difference of the degree of RH between the mild and severe asphyxia infants. ConclusionMaternal thrombocytopenia was a risk factor of RH and associated with the occurrence of severe RH. Meanwhile, vaginal delivery,suffocation were also risk factors of RH.

参考文献/References:

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更新日期/Last Update: 2016-12-25