[1]杨帆*,谢承志.高强度聚合超声联合促性腺激素释放激素激动剂治疗子宫腺肌病的疗效及对血红蛋白水平的影响[J].中国计划生育和妇产科,2017,(5):64-68.
　YANG Fan*,XIE Cheng-zhi.Effect of high intensity focused ultrasound combined with GnRHa on adenomyosis and its effect on hemoglobin level[J].Chinese Journal of Family Planning & Gynecotokology,2017,(5):64-68.
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高强度聚合超声联合促性腺激素释放激素激动剂治疗子宫腺肌病的疗效及对血红蛋白水平的影响
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2017年5期
页码:
64-68
栏目:
论著与临床
出版日期:
2017-05-25

文章信息/Info

Title:
Effect of high intensity focused ultrasound combined with GnRHa on adenomyosis and its effect on hemoglobin level
作者:
杨帆1*; 谢承志2
1. 434020湖北荆州，荆州市第五人民医院妇产科；2. 430056湖北黄石，黄石市第四医院妇产科
Author(s):
YANG Fan1*;  XIE Cheng-zhi2
1.Department of Obstetrics and Gynecology, Jingzhou Fifth People's Hospital, Jingzhou Hubei 434020, P.R.China;2.Department of Obstetrics and Gynecology, Huangshi Fourth Hospital, Huangshi Hubei 430056, P.R.China
关键词:
高强度聚合超声; 促性腺激素释放激素激动剂; 子宫腺肌病; 临床疗效
Keywords:
HIFU;  GnRHa;  adenomyosis;  clinical efficacy
分类号:
R 711.74
摘要:
目的研究高强度聚合超声(high intensity focused ultrasound，HIFU)联合促性腺激素释放激素激动剂(gonadotropin-releasing hormone agonist，GnRHa)治疗子宫腺肌病(adenomyosis，AM)的临床疗效。方法选取湖北省妇幼保健院2014年2月至2015年5月收治的AM患者114例，采用随机数字表法将其分为联合组、HIFU组及GnRHa组3组，每组各38例，其中HIFU组采用HIFU治疗，GnRHa组采用GnRHa治疗，联合组则采用
Abstract:
ObjectiveTo study the effect of high intensity focused ultrasound(HIFU) combined with gonadotropin-releasing hormone agonist(GnRHa) on adenomyosis(AM). Methods114 AM patients in Hubei Maternal and Child Health Care Hospital from February 2014 to May 2015 were selected as the research object, and were randomly divided into three groups:HIFU group, GnRHa group and combined group, with 38 cases in each group. The HIFU group were treated with HIFU, the GnRHa group were treated with GnRHa and combined group were treated with HIFU combined with GnRHa respectively. Lesion size, degree of dysmenorrhea, uterine volume and serum hemoglobin(Hb) levels of 3 months, 6 months and 12 months before and after treatment were measured and compared in the three groups. Results3 months, 6 months and 12 months after treatment, lesion area, uterine volume and dysmenorrhea score of the combined group were significantly lower than the HIFU group and GnRHa group.While the blood Hb levels were significantly higher than before treatment in the three groups, and were higher in the combined group than in the HIFU group and GnRHa group. The differences were statistically significant(P<005). ConclusionHIFU combined with GnRHa treatment of AM was significantly better than HIFU and GnRHa treatment alone. It can significantly reduce patients' dysmenorrhea, reduce the lesion size, to promote the uterus to restore its normal volume, and also significantly improve blood Hb levels.It is worthy of clinical promotion.

参考文献/References:

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更新日期/Last Update: 2017-05-25