[1]施瑾,陈芷青*.妊娠期高血压疾病患者血浆生长分化因子-15 水平的测定及临床意义[J].中国计划生育和妇产科,2017,(5):48-51.
　SHI Jin,CHEN Zhi-qing*.Determination and clinical significance of plasma growth differentiation factor - 15 in hypertensive disorders complicating pregnancy[J].Chinese Journal of Family Planning & Gynecotokology,2017,(5):48-51.
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妊娠期高血压疾病患者血浆生长分化因子-15 水平的测定及临床意义
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2017年5期
页码:
48-51
栏目:
论著与临床
出版日期:
2017-05-25

文章信息/Info

Title:
Determination and clinical significance of plasma growth differentiation factor - 15 in hypertensive disorders complicating pregnancy
作者:
施瑾; 陈芷青*
海门市人民医院妇科
Author(s):
SHI Jin; CHEN Zhi-qing*
Department of Gynaecology and Obstetrics , Haimen People 's Hospital, Haimen Jiangsu 226100, P.R. China
关键词:
妊娠期高血压疾病; 子痫; 生长分化因子-15
Keywords:
hypertensive disorders complicating pregnancy;  preeclampsia;  GDF-15
分类号:
R 714.252
摘要:
目的探讨孕妇血浆生长分化因子-15 (plasma growth differentiation factor-15，GDF-15)在妊娠期高血压疾病中的预测和诊断价值。方法选择2014年7月至2016年6月在海门市人民医院就诊及住院分娩的妊娠期高血压疾病孕妇137例，包括妊娠期高血压61例，轻度子痫前期28例，重度子痫前期27例，慢性高血压21例。另有同期在我院产前检查及住院分娩的正常单胎孕妇120例。所有正常孕妇及各组妊娠期高血压疾病孕妇分别按孕20周前、20～27周、28～35周、36周后再分组并
Abstract:
ObjectiveTo discuss the predictive and diagnostic value of plasma growth differentiation factor-15 (GDF-15) in women with hypertensive disorders complicating pregnancy.Methods137 women with hypertensive disorders complicating pregnancy including 61 gestational hypertension, 28 mild preeclampsia,27 severe preeclampsia and 21 chronic hypertension complicating pregnancy hospitlized in Haimen People's Hospital from July 2014 to June 2016 were collected. They were divided into four groups according to severity of disease. 120 normal pregnant women were collected over the same time as the control group. Testing the plasma GDF-15 in all women. Then, every group were further divided into 4 groups according to different gestational age as less than 20 weeks,20～27 weeks,28～35 weeks and more than 36 weeks. ResultsPlasma GDF-15 in preeclampsia group was significantly higher than other groups. Among them the severe group was higher than the mild group(P＜005）.GDF-15 in the gestational age more than 36 weeks group was significantly higher than that in gestational age less than 20 weeks,20～27weeks and 28～35weeks groups in severe preeclampsia pregnant(P＜005）. There were no differences in other groups throughout the pregnancy(P﹥005）.ConclusionGDF-15 maybe a potential predictor of severity in hypertensive disorders complicating pregnancy.

参考文献/References:

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更新日期/Last Update: 2017-05-25