[1]张兰,张波,邱艳,等.甲氨蝶呤联合米非司酮治疗未破裂型输卵管妊娠的价值[J].中国计划生育和妇产科,2010,(06):0.
 ZHANG Lan,ZHANG Bo,QIU Yan..[J].Chinese Journal of Family Planning & Gynecotokology,2010,(06):0.
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甲氨蝶呤联合米非司酮治疗未破裂型输卵管妊娠的价值
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2010年06期
页码:
0
栏目:
论著与临床
出版日期:
2010-12-30

文章信息/Info

作者:
张兰张波邱艳
巴中市中心医院妇产科;双流贸园医院妇产科;四川省妇女儿童医院妇产科;
Author(s):
ZHANG Lan1ZHANG Bo2QIU Yan31.
Department of Obstetrics and Gynecology,Bazhong Central Hospital,Bazhong Sichuan 636000,China;2.Department of Obstetrics and Gyneclolgy,Maoyuan Hospital in,China Shuangliu county,Chengdu city,Chengdu Sichuan 610200,China;3. Department of Obstetrics and Gynecology,Sichuan Provincal Women and Children Hospital,Chengdu Sichuan 610031,China
关键词:
甲氨蝶呤米非司酮未破裂型输卵管妊娠治疗
分类号:
R714.221
摘要:
目的探讨甲氨蝶呤(methotrexate,MTX)联合米非司酮治疗输卵管妊娠的临床价值。方法对未破裂型输卵管妊娠患者127例随机分为观察组(63例)及对照组(64例)两组,观察组:MTX肌肉注射,0.4mg/kg×5d,米非司酮口服,50mg/次,2次/d,共6d;对照组:MTX肌肉注射,0.4mg/kg×5d,同时口服安慰剂1片,2次/d,共5天。治疗期间严密观察阴道流血、血β-人绒毛膜促性腺激素(β-humanchorionic gona-dotrophin,β-HCG)值降至正常时间及异位妊娠包块吸收时间,比较两组间的差异。结果平均住院时间、血β-HCG降至正常时间和异位妊娠包块的直径缩小观察组均明显优于对照组,差异具有统计学意义(P<0.05)。两组间在不良反应方面差异无统计学意义。结论 MTX联合米非司酮可提高未破裂型输卵管妊娠的治疗成功率,优于单用MTX,值得临床推广应用。

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更新日期/Last Update: 2010-12-30