[1]张美华,张艳萍,盖凌,等.孕妇外周血与新生儿脐带血内皮祖细胞数量及功能分析[J].中国计划生育和妇产科,2012,(04):0.
 ZHANG Mei-hua,ZHANG Yan-ping,GAI Ling,et al.[J].Chinese Journal of Family Planning & Gynecotokology,2012,(04):0.
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孕妇外周血与新生儿脐带血内皮祖细胞数量及功能分析
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2012年04期
页码:
0
栏目:
论著与临床
出版日期:
2012-08-30

文章信息/Info

作者:
张美华张艳萍盖凌张爱东邱毅
山东省计划生育科学技术研究所·山东省优生技术重点实验室;
Author(s):
ZHANG Mei-huaZHANG Yan-pingGAI LingZHANG Ai-dongQIU Yi* Key Laboratory for Improving Birth Outcome TechniqueShandong Provincial Family Planning
Institute of Science and Technology,Ji’nan Shangdong 250002,P.R.China
关键词:
内皮祖细胞孕妇外周血脐带血
分类号:
R329
摘要:
目的观察孕妇外周血和新生儿脐带血内皮祖细胞(endothelial progenitor cells,EPCs)数量和功能变化的相关性。方法用流式细胞仪检测未怀孕妇女和早孕妇女外周血中内皮祖细胞的数量;用密度梯度离心法分离脐带血内皮祖细胞;用流式细胞仪检测脐带血内皮祖细胞的数量;脐带血内皮祖细胞经体外培养7d后,分组做增殖实验、迁移实验和粘附实验。结果妇女怀孕后循环中内皮祖细胞数量增加;外周血内皮祖细胞数量明显降低的孕妇所产新生儿的脐带血内皮祖细胞数量降低,增殖、迁移和粘附能力下降,与对照组比较差异有统计学意义(P<0.05)。结论怀孕后循环内皮祖细胞数量增加明显;孕妇外周血和新生儿脐带血内皮祖细胞的数量和功能变化有一定的相关性。

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备注/Memo

备注/Memo:
山东省人口科技发展项目(200706)
更新日期/Last Update: 2012-08-30