[1]何茜冬,唐妍,郑妍,等.诱发排卵治疗中血清白细胞介素-6对卵巢过度刺激综合征的预测作用[J].中国计划生育和妇产科,2014,(05):0.
 HE Qian-dong,TANG-Yan,ZHENG-Yan,et al.[J].Chinese Journal of Family Planning & Gynecotokology,2014,(05):0.
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诱发排卵治疗中血清白细胞介素-6对卵巢过度刺激综合征的预测作用
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2014年05期
页码:
0
栏目:
论著与临床
出版日期:
2014-10-31

文章信息/Info

作者:
何茜冬唐妍郑妍黄彦清欧美珍
中山市人民医院妇产科;
Author(s):
HE Qian-dong;TANG-Yan;ZHENG-Yan;HUANG Yan-qing;OU Mei-zhen;
Department of gynecology and Obstetrics,Zhongshan City People’s Hospital;
关键词:
白细胞介素-6雌二醇卵巢过度刺激综合征
分类号:
R714.8
摘要:
目的探讨诱发排卵的门诊患者人绒毛膜促性腺激素(human chorionic,gonadotropin,HCG)日血清白细胞介素-6(interleukin,IL-6)对卵巢过度刺激综合征(ovarian hyperstimulation syndrome,OHSS)发生的预测价值。方法根据是否发生OHSS将165例患者分为两组,OHSS组23例,非OHSS组142例,分别检测诱发排卵周期中HCG日血清雌二醇(estradiol,E2)、IL-6水平及≥14 mm卵泡数,进行对比分析,并采用ROC曲线分别评价三者对OHSS发生的预测价值。结果 OHSS组患者HCG日血清IL-6、E2水平和≥14 mm卵泡数显著高于非OHSS组(P<0.05),分别为(187.0±34.6 vs 110.5±30.0)pg/mL、(1 563.5±626.0 vs 587.1±384.6)pg/mL、(5.0±1.4 vs 1.7±0.9)个。ROC曲线分析结果显示ROC曲线下面积IL-6为0.951(95%CI:0.895~1.006,P<0.001);E2为0.913(95%CI:0.860~0.9660,P<0.001);≥14 mm卵泡数为0.974(95%CI:0.943~1.004,P<0.001)。结论在诱发排卵的不孕患者中,HCG日血清IL-6的水平也可用于预测OHSS的发生。

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更新日期/Last Update: 2014-10-30