[1]徐红.拉贝洛尔对早发型重度子痫前期患者子宫螺旋动脉血流动力学及胎盘微血管密度的影响观察[J].中国计划生育和妇产科,2017,(9):41-43.
　XU Hong.Observation on the influence of labetalol on the uterine spiral artery hemodynamics and placental vascular density of patients with early-onset severe preeclampsia[J].Chinese Journal of Family Planning & Gynecotokology,2017,(9):41-43.
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拉贝洛尔对早发型重度子痫前期患者子宫螺旋动脉血流动力学及胎盘微血管密度的影响观察
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2017年9期
页码:
41-43
栏目:
论著与临床
出版日期:
2017-09-25

文章信息/Info

Title:
Observation on the influence of labetalol on the uterine spiral artery hemodynamics and placental vascular density of patients with early-onset severe preeclampsia
作者:
徐红
武警湖北总队医院妇产科
Author(s):
XU Hong
Department of Obstetrics and Gynecology, Wuhan Armed Police Corps Hospital of Hubei province, Wuhan Hubei 430061,P.R.China
关键词:
拉贝洛尔; 早发型重度子痫前期; 子宫螺旋动脉; 血流动力学; 胎盘微血管密度; 影响
Keywords:
labetalol; early-onset severe preeclampsia; uterine spiral artery; hemodynamics; placental vascular density; influence
分类号:
R 714.24+5
摘要:
目的探讨拉贝洛尔对早发型重度子痫前期患者子宫螺旋动脉血流动力学及胎盘微血管密度的影响。方法将2013~2016年于武警湖北总队医院进行治疗的92例早发型重度子痫前期患者按随机数字表分为对照组与观察组，各46例，两组均以硫酸镁进行治疗，在此基础上对照组加用硝苯地平口服治疗，观察组则加用拉贝洛尔治疗，比较两组患者治疗前与治疗后1、3、5 d的子宫螺旋动脉血流动力学及胎盘微血管密度。结果观察组治疗后1、3、5 d的子宫螺旋动脉血流动力学指标均显著优于对照组，胎盘蜕膜及绒毛微血管密度也高于对照组，差异有统计学意义
Abstract:
ObjectiveTo investigate the influence of labetalol on the uterine spiral artery hemodynamics and placental vascular density of patients with early-onset severe preeclampsia. Methods92 patients with early-onset severe preeclampsia in Wuhan Armed Police Cor

参考文献/References:

［1］陈洲芳．拉贝洛尔联合硫酸镁治疗早发型重度子痫前期疗效观察 ［J］．中国基层医药，2011，18 （16）：2231-2232． ［2］姚兰，黎丽，王晓怡．拉贝洛尔与硝酸甘油治疗重度子痫前期的疗效对比研究 ［J］．中国医师杂志，2011，13 （7）：986-988． ［3］王占山．拉贝洛尔联用硫酸镁治疗早发型重度子痫前期132例临床分析 ［J］．中国煤炭工业医学杂志，2011，14 （4）：543-544． ［4］张鸿．硫酸镁联合可拉贝洛尔治疗早发型重度子痫前期的临床观察 ［J］．中国初级卫生保健，2011，25 （4）：108-109． ［5］Naruse K, Sado T, Noguchi T, et al. Peripheral RAGE (receptor for advanced glycation endproducts)-ligands in normal pregnancy and preeclampsia: novel markers of inflammatory response ［J］. J Reprod Immunol, 2012, 93 (2): 69-74. ［6］蔡冰．硫酸镁联合拉贝洛尔治疗子痫前期66例临床分析 ［J］．山东医药，2008，48 （4）：96． ［7］Kodama M, Miyoshi H, Fujito N, et al. Plasma mRNA concentrations of placenta-specific 1 (PLAC1) and pregnancy associated plasma protein A (PAPP-A) are higher in early-onset than lateonset preeclampsia［J］. J Obstet Gynaecol Res, 2011, 37(4): 313-318. ［8］张薇．硫酸镁对子痫前期患者子宫动脉、螺旋动脉及胎儿血流动力学指标的影响研究［J］．海峡药学，2012，24（10）：243-244．

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更新日期/Last Update: 2017-09-25