[1]李瑞琼*,辜素梅,杨丽红.糖化血红蛋白水平在预测妊娠期糖尿病孕妇生产结局中的价值分析[J].中国计划生育和妇产科,2017,(10):48-50,54.
 LI Rui-qiong*,GU Su-mei,YANG Li-hong.Value of glycosylated hemoglobin level in predicting pregnancy outcomes of gestational diabetes mellitus[J].Chinese Journal of Family Planning & Gynecotokology,2017,(10):48-50,54.
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糖化血红蛋白水平在预测妊娠期糖尿病孕妇生产结局中的价值分析
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2017年10期
页码:
48-50,54
栏目:
论著与临床
出版日期:
2017-10-25

文章信息/Info

Title:
Value of glycosylated hemoglobin level in predicting pregnancy outcomes of gestational diabetes mellitus
作者:
李瑞琼* 辜素梅杨丽红
眉山市妇幼保健院产科
Author(s):
LI Rui-qiong*GU Su-meiYANG Li-hong
Department of Obstetrics and Gynecology, Meishan Women and Children’s Hospital,Meishan Sichuan 620010,P.R.China
关键词:
妊娠期糖尿病糖化血红蛋白预测妊娠结局
Keywords:
gestational diabetes mellitus glycosylated hemoglobin predition pregnancy outcomes
分类号:
R 714.256
摘要:
目的探讨糖化血红蛋白(glucosylated hemoglobin,HbAlc)水平在预测妊娠期糖尿病(gestational diabetes mellitus,GDM)孕妇生产结局中的价值。方法将2014年6月至2015年12月在四川省眉山市妇幼保健院进行产前检查并在该院分娩的146例GDM孕妇,按照分娩前HbAlc水平控制情况将其分为控制组86例、未控制组60例,另外选取同期HbAlc水平正常的产妇60例作为对照组,对比分析3组产妇妊娠结局。结果未控制组妊娠期高血压疾病、胎膜早破、羊水过多、剖宫产率、羊水粪染、早产、胎儿宫内窘迫、新生儿窒息和巨大儿发生率明显高于控制组和对照组(P<005),控制组和对照组比较差异无统计学意义(P>005)。 结论HbAlc水平对GDM孕妇的妊娠结局有较好的预测作用,可将HbAlc水平作为孕妇血糖控制情况的重要监测指标。
Abstract:
ObjectiveTo investigate the value of glycosylated hemoglobin (HbAlc) level in predicting the outcomes of pregnant women with gestational diabetes mellitus(GDM). Methods146 pregnant women diagnosed with GDM in Meishan Women and Children’s Hospital from June 2014 to December 2015 were divided into control group(86 cases) and non-control group(60 cases). 60 women with normal HbAlc levels were selected as the matched group. The pregnancy outcomes of the three groups were analyzed. ResultsThe proportion of pregnancy induced hypertension, premature rupture of membranes, polyhydramnios, cesarean section, meconium stained amniotic fluid, premature delivery, fetal distress, neonatal asphyxia and giant baby in non-control group were significantly higher than that of the control group and the matched group, the differences were statistically significant(P< 005).While the differences between the control group and the matched group had no statistical significance(P>005).ConclusionThe level of HbAlc has a good predictive effect on the production of GDM pregnant women.It can be used as an important monitoring index of blood glucose control in pregnant women with GDM.

参考文献/References:

[1]SHEHADEH N, MAOR Y, Ramadan Study Group Effect of a new insulin treatment regimen on glycaemic control and quality of life of Muslim patients with type 2 diabetes mellitus during Ramadan fast - an open label, controlled, multicentre, cluster randomised study [J] International Journal of Clinical Practice, 2015, 69 (11) : 1281-1288. [2]汪漪.妊娠期糖尿病与妊娠结局的关系 [D].苏州:苏州大学,2014. [3]杨慧霞.妊娠期糖尿病新诊断标准应用后面临的问题 [J].中国妇产科临床杂志,2012,13(3):161-162. [4]中华医学会妇产科学分会产科学组.中华医学会围产医学分会妊娠合并糖尿病协作组.妊娠合并糖尿病诊治指南(2014) [J].中华妇产科杂志,2014,49(8):561-569. [5]刘智慧.糖化血红蛋白联合甘油三酯对妊娠期糖尿病的早期预测 [J].中国药物与临床,2014,14(8):1133-1134. [6]LOWE L P, METZGER B E, DYER A R, et al. Hyperglycemia and adverse pregnancy outcome (HAPO) study: associations of maternal A1C and glucose with pregnancy outcomes [J]. Diabetes Care, 2012, 35 (3) : 574-580. [7]徐国宾.糖尿病诊断标准的完善及糖化血红蛋白A1C检测的标准化 [J].临床检验杂志,2012,30(6):401-405. [8]孙延祯,马亚娜,雷婷,等.糖化血红蛋白对妊娠期糖尿病诊断价值的Meta分析 [J].中国妇幼保健,2011,26(9):1428-1430. [9]俞恒.孕妇外周血糖化血红蛋白检测在妊娠期糖尿病诊断中的价值探讨 [J].中国实验诊断学,2016,20(4):586-588. [10]蔡慧华,何援利,王雪峰,等.糖化血红蛋白联合空腹血糖检测在妊娠期糖尿病筛查中的应用价值 [J].实用妇产科杂志,2014,30(3):205-208. [11]王海霞.妊娠期糖尿病患者糖化血红蛋白水平与不良妊娠结局的关系 [J].中国医药导报,2015,12(26):74-77. [12]马永萍,李娟,马小云.妊娠期糖尿病孕妇糖化血红蛋白水平与母婴结局的关系 [J].现代妇产科进展,2016,25(2):127-130. [13]周建良.妊娠期糖尿病88例临床研究 [J].中外医学研究,2014,12(4):142-143. [14]钟丽君,王永周,汪静.糖化血红蛋白水平检测与妊娠期糖尿病孕妇妊娠结局相关性分析 [J].标记免疫分析与临床,2016,23(1):68-70.

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更新日期/Last Update: 2017-10-25