[1]林莉,王晨,苏日娜,等.我国不同城市妊娠晚期贫血的患病状况、相关因素及妊娠结局分析[J].中国计划生育和妇产科,2018,(8):37-40,49.
　LIN Li,WANG Chen,SU Ri-na,et al.Prevalence, risk factors and associated outcomes of anemia among late pregnancy in different cities of China[J].Chinese Journal of Family Planning & Gynecotokology,2018,(8):37-40,49.
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我国不同城市妊娠晚期贫血的患病状况、相关因素及妊娠结局分析
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2018年8期
页码:
37-40,49
栏目:
论著与临床
出版日期:
2018-08-25

文章信息/Info

Title:
Prevalence, risk factors and associated outcomes of anemia among late pregnancy in different cities of China
作者:
林莉; 王晨; 苏日娜; 冯慧; 杨慧霞*
北京大学第一医院妇产科
Author(s):
LIN Li;  WANG Chen;  SU Ri-na;  FENG Hui;  YANG Hui-xia*
Department of Obstetrics & Gynecology, Peking University First Hospital, Beijing 100034, P.R.China.
关键词:
贫血; 妊娠晚期; 患病率; 高危因素; 妊娠结局
Keywords:
anemia;  pregnancy; prevalence; risk factors;  pregnancy outcomes
分类号:
R 714.254
摘要:
目的调查我国3大城市妊娠晚期贫血危险因素及其对妊娠结局的影响。方法回顾性分析2013年6月至2015年5月在3个城市21家医院分娩，且有晚孕期（检测孕周≥28周）血红蛋白（hemoglobin,Hb）记录的39 454例单胎孕妇的病例资料，根据世界卫生组织推荐，将孕妇分为贫血组（Hb<110 g/L）与非贫血组（Hb≥110 g/L）。对贫血的患病率、相关危险因素及妊娠结局进行回顾性分析。结果妊娠晚期贫血的总体患病率为164 %（6 485/39 454），其中北京市、广州市和成都市的患病率分别为123 %、327 %及156 %。贫血发生的危险因素包括年轻偏瘦女性、经产妇、农村户籍、受教育程度低及家庭收入偏低者。贫血组的早产（83 %）、低出生体重儿（51 %）及新生儿转儿科（98 %）的发生率均高于非贫血组（49 %、34 %及61 %），差异均有统计学意义（P<005）。但贫血组妊娠期糖尿病（158 %）和胎儿窘迫的发生率（95%）较非贫血组（198 %、125%）低，差异均有统计学意义（P<005）。剖宫产、妊娠期高血压疾病、子痫前期中度贫血组与非贫血组相比，疾病的发生率显著增加；而胎膜早破及巨大儿方面，两组差异无统计学意义(P>005)。结论我国孕妇妊娠晚期贫血的高患病率与不良妊娠结局息息相关。
Abstract:
ObjectiveTo investigate the related risk factors and adverse outcomes of anemia among late pregnancy in 3 cities of Chinese women. MethodsA retrospective analysis was conducted on 39 454 singleton pregnant women from June 2013 to May 2015 in 21 hospitals from 3 cities in China. Hemoglobin(Hb) level were determined in all of these women at the third trimester(≥28 weeks). Demographic data and medical information were collected individually through questionnaires. The recruited gravidas were divided into anemic group(Hb<110g/L) and non-anemic group(Hb≥110g/L) according to the recommendations of World Health Organization(WHO). The incidence of anemia, risk factors，perinatal outcome and complications in mother and infant were compared between the two groups. ResultsThe prevalence of anemia at the third trimester in total is 164 %(6 485/39 454). As for different area, the incidence of anemia in Beijing, Guangzhou and Chengdu was 123 %，327 % and 156 % respectively.Young women with lower pre-pregnancy BMI level, multipara, less educated status, lower income and rural resident were high risk factors for anemia.The incidences of preterm labor(83 %),low birth weight(51 %)and neonatal ward admission(98 %)were all significantly higher in anemic group than in non-anemic group(49 %,34 % and 61 %)(P<005). The incidence of GDM（158 %）and fetal distress(95 %) was lower in anemic group than non-anemic group (198 %, 125 %,P<005). The incidences of cesarean section, hypertensive disorders and preeclampsia were higher in moderate anemic group than non-anemic group. There were no significant different of incidence of premature rupture of membrane and macrosomia between two groups. ConclusionAnemia continues to be a severe health problem among pregnant women in China, which is related to adverse outcomes.

参考文献/References:

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备注/Memo

备注/Memo:
世界糖尿病基金（项目编号：WDF10-57，WDF14-908）; 国家科技支撑计划(项目编号：2015BAI13B06）
更新日期/Last Update: 2018-08-25