[1]夏小凤,马子凤,胡咏梅,等.基于微信平台的健康指导在不明原因不孕症体外受精/卵胞浆内单精子显微注射技术治疗中的作用探讨[J].中国计划生育和妇产科,2020,(1):52-56.
　XIA Xiao-feng,MA Zi-feng,HU Yong-mei,et al.Discussion on the role of health guidance based on WeChat platform in infertility of unknown reason in vitro fertilization/intracytoplasmic sperm microinjection technology treatment[J].Chinese Journal of Family Planning & Gynecotokology,2020,(1):52-56.
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基于微信平台的健康指导在不明原因不孕症体外受精/卵胞浆内单精子显微注射技术治疗中的作用探讨
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2020年1期
页码:
52-56
栏目:
论著与临床
出版日期:
2020-01-25

文章信息/Info

Title:
Discussion on the role of health guidance based on WeChat platform in infertility of unknown reason in vitro fertilization/intracytoplasmic sperm microinjection technology treatment
作者:
夏小凤; 马子凤; 胡咏梅; 赵程程; 檀仙; 李张静; 高冉冉*
解放军联勤保障部队第901医院生殖医学中心
Author(s):
XIA Xiao-feng; MA Zi-feng; HU Yong-mei; ZHAO Cheng-cheng; TAN Xian; LI Zhang-jing; GAO Ran-ran*
Reproductive Medicine Center,901st Hospital of the PLA Joint Operations Support Force, Hefei Anhui 230031,P.R.China
关键词:
不孕症; 体外受精; 卵胞浆内单精子显微注射技术; 微信平台; 健康指导
Keywords:
infertility;  in vitro fertilization;  intracytoplasmic sperm microinjection;  WeChat platform;  health guidance
分类号:
R 473.71
摘要:
目的探讨基于微信平台的健康指导在不明原因不孕症体外受精（in vitro fertilization，IVF）/卵胞浆内单精子显微注射技术（intracytoplasmic sperm injection，ICSI）治疗中的作用效果。方法以等距随机抽样法将解放军联勤保障部队第901医院2018年1月至2019年1月收治的80例行IVF/ICSI治疗的不明原因不孕症患者分为对照组（常规健康宣教）和观察组（基于微信平台的健康指导），各40例，对两组心理状态评分（焦虑评分、抑郁评分）、Olson婚姻质量评分、FertiQoL生活质量评分、睡眠质量评分、生育压力评分、血清单胺类神经递质浓度（去甲肾上腺素、多巴胺、5-羟色胺）、优质胚胎率、临床妊娠率、活产率、护理满意度进行对比。结果干预前两组心理状态评分、Olson婚姻质量评分、FertiQoL生育生活质量评分、睡眠质量评分、生育压力评分、血清单胺类神经递质浓度差异无统计学意义（P＞005），干预后心理状态评分、睡眠质量评分、生育压力评分较干预前下降，Olson婚姻质量评分、FertiQoL生活质量评分、血清单胺类神经递质浓度较干预前上升，差异均有统计学意义（P＜005），观察组心理状态、睡眠质量评分、生育压力评分低于对照组，Olson婚姻质量评分、FertiQoL生活质量评分、血清单胺类神经递质浓度高于对照组，差异有统计学意义（P＜005）；两组护理满意度分别为9250 %、8000 %，观察组高于对照组，差异有统计学意义（P＜005）。结论在不明原因不孕症IVF/ICSI治疗中基于微信平台的健康指导有助于进一步改善患者负性心理状态，提高生活质量及婚姻质量，增强疗效并提高活产率，为构建和谐护患关系提供帮助，值得在今后临床工作中推广使用。
Abstract:
ObjectiveTo explore the effect of health guidance based on WeChat platform in the treatment of unexplained infertility in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI). Methods80 patients with unexplained infertility who underwent IVF/ICSI treatment from January 2018 to January 2019 in 901st Hospital of the PLA Joint Operations Support Force were divided into a control group with routine health education and a WeChat-based platform. The health-directed observation group consisted of 40 patients with a mental state score (anxiety score, depression score), Olson marital quality score, FertiQoL quality of life score, sleep quality score, fertility stress score, serum monoamine neurotransmitter concentration(norepinephrine, dopamine, serotonin), high quality embryo rates, clinical pregnancy rates, live birth rates,nursing satisfaction comparison. ResultsThere were no significant differences in psychological state scores, Olson marital quality scores, FertiQoL reproductive quality of life scores, sleep quality scores, birth stress scores, and serum monoamine neurotransmitters concentrations before intervention (P>005). The state score, sleep quality score, and fertility stress score decreased compared with the pre-intervention. The Olson marital quality score, FertiQoL quality of life score, and serum monoamine neurotransmitter concentration were significantly higher than those before the intervention (P<005). The group's psychological state, sleep quality score, and fertility stress score were lower than the control group. The Olson marital quality score, FertiQoL quality of life score, and serum monoamine neurotransmitter concentration were higher than the control group, and there was statistical difference (P<005). The high quality embryo rate, clinical pregnancy rate, live birth rate in the observation group were higher than those in the control group (P<005).The satisfaction of group nursing was 9250 % and 8000 %, respectively. There was statistical difference between the observation group and the control group (P<005). ConclusionHealth guidance based on WeChat platform in IVF / ICSI treatment of unexplained infertility can further improve the negative psychological state of patients, improve the quality of life and marriage, enhance the efficacy and increase the live birth rate, and provide a harmonious relationship between nurses and patients, worthy of popularization and use in future clinical work.

参考文献/References:

［1］余芝芝，吴瑞芳，傅晓华，等．宫、腹腔镜联合探查对原因不明性不孕诊断及临床疗效 ［J］．中国计划生育学杂志，2019，27（6）：742-746． ［2］VANHOOGENHUIJZE N E, TORRANCE H L, MOL F, et al. Endometrial scratching in women with implantation failure after a first IVF/ICSI cycle，does it lead to a higher live birth rate?The SCRaTCH study:a randomized controlled trial(NTR 5342) ［J］. BMC Women's Health, 2017, 17(1): 47. ［3］倪颖，童琛晔，韩迟迟，等．体外受精-胚胎移植患者电子信息化健康教育模式的构建和效果评价 ［J］．中华生殖与避孕杂志，2019，39（5）：399-402． ［4］华静，郑剑兰．体外授精-胚胎移植,卵胞浆内单精子显微注射技术与妊娠期高血压疾病的相关性分析 ［J］．中国妇幼保健，2017，32（19）：4780-4782． ［5］王蕾，颜晓红，林莉，等．高龄不孕妇女辅助生殖助孕前心理状况调查 ［J］．中华生殖与避孕杂志，2019，39（6）：448-452． ［6］谢雅琴,肖红,柳鸣, 等.行辅助生殖技术治疗的高龄不孕女性生育二胎的心理健康相关因素分析 ［J］.中华生殖与避孕杂志,2016,36(12):1031-1035,1039. ［7］张妍，贾博钦，常丽媛，等．天津地区育龄期女性不孕症流行病学调查 ［J］．中国计划生育学杂志，2016，24（5）：301-305． ［8］丛丰辉，韩璐，郭丹．不孕症夫妻心理状况及应对方式的研究 ［J］．中国实用护理杂志，2018，34（5）：373-377． ［9］郭启云，颜丹，刘颖，等．体外受精胚胎移植患者焦虑、抑郁情绪与生育生命质量的相关性分析 ［J］．中国实用护理杂志，2017，33（27）：2081-2086． ［10］牟万宏．人工授精对接受精子-透明质酸结合试验的原因不明性不孕患者妊娠结局及人绒毛膜促性腺激素、孕酮水平的影响 ［J］．中国妇幼保健，2018，33（2）：402-404． ［11］郭鹏，陈玉玲．自拟滋补肝肾组方对女性更年期综合征患者血管舒缩功能失调及单胺类神经递质的影响 ［J］．中国妇幼保健，2019，34（3）：596-601． ［12］李国樑，郑杰蔚，殷霄，等．1,2-二氯乙烷亚急性暴露对大鼠抑郁样行为及单胺神经递质水平的影响 ［J］．中国职业医学，2019，46（2）：152-156． ［13］AGOSTINI F, MONTI F, PATERLINI M, et al. Effect of the previous reproductive outcomes in subfertile women after in vitro fertilization(IVF)and/or intracytoplasmic sperm injection(ICSI)treatments on perinatal anxious and depressive symptomatology ［J］. Journal of Psychosomatic Obstetrics and Gynaecology, 2018, 39(1): 29-37. ［14］李金英，周军．基于微信平台对化疗间歇期PICC置管患者的延续性护理效果研究 ［J］．中国实用护理杂志，2018，34（36）：2843-2846． ［15］王兆锦，林志娟，马鹤星．基于微信移动平台的专业化个案管理在乳腺癌病人延伸服务中的应用效果 ［J］．护理研究，2019，33（3）：524-527．

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　FANG Wei-fen,TAN Da-xian Population and family planning research center of Guangxi autonomous region,Nanning Guangxi 00,et al.[J].Chinese Journal of Family Planning & Gynecotokology,2009,(1):0.
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更新日期/Last Update: 2020-01-25