[1]陈庆梅,敖强*.妊娠晚期非糖尿病孕妇血脂水平对巨大儿的 预测价值[J].中国计划生育和妇产科,2020,(4):45-48.
 CHEN Qing mei,AO Qiang*.The predictive value of blood lipids levels at late pregnancy for macrosomia in women without diabetes mellitus[J].Chinese Journal of Family Planning & Gynecotokology,2020,(4):45-48.
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妊娠晚期非糖尿病孕妇血脂水平对巨大儿的 预测价值
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《中国计划生育和妇产科》[ISSN:1674-4020/CN:51-1708/R]

卷:
期数:
2020年4期
页码:
45-48
栏目:
论著与临床
出版日期:
2020-04-25

文章信息/Info

Title:
The predictive value of blood lipids levels at late pregnancy for macrosomia in women without diabetes mellitus
作者:
陈庆梅敖强*
宜宾市第一人民医院屏山院区妇产科
Author(s):
CHEN Qingmei AO Qiang*
Department of Obstetrics and Gynecology, the First People's Hospital of Yibin, Yibin Sichuan 645350,P.R.China
关键词:
妊娠晚期血脂巨大儿
Keywords:
late pregnancy blood lipid macrosomia
分类号:
R 7142
摘要:
目的 探讨妊娠晚期非糖尿病孕妇血脂水平与巨大儿的关系。 方法 回顾性分析2016年2月至2019年3月在宜宾市第一人民医院屏山院区产科住院分娩的1 200例妊娠孕妇的病历资料。根据新生儿出生体重将受试者分为巨大儿组(126例)和对照组(1 074例)。比较两组临床资料,采用Logistic回归模型分析妊娠晚期血脂水平对巨大儿发生的相关性及其风险;绘制受试者工作特征(ROC)曲线评估妊娠晚期非糖尿病孕妇血脂水平对巨大儿发生的预测效能。结果 两组孕妇血清总胆固醇水平组间比较差异无统计学意义(P>005);巨大儿组孕妇血清甘油三酯(triglyceride, TG)、低密度脂蛋白胆固醇水平高于对照组(P<005);巨大儿组孕妇血清高密度脂蛋白胆固醇(high density liptein cholesterol,HDLC)水平低于对照组(P<005);Logistic回归分析显示,妊娠晚期非糖尿病孕妇血清TG、HDLC水平是巨大儿发生的独立危险因素(P<005);ROC曲线分析显示,妊娠晚期非糖尿病孕妇血清TG、HDLC水平对巨大儿发生具有预测价值(P<005),曲线下面积为0878,敏感度为954 %,特异度为684 %。 结论 妊娠晚期非糖尿病孕妇血清TG、HDLC水平与巨大儿发生密切相关,对巨大儿发生具有良好预测价值。
Abstract:
ObjectiveTo explore the relationship between blood lipid level and macrosomia in women without diabetes mellitus at late pregnancy. Methods From February 2016 to March 2019, the medical records of 1 200 pregnant women in the First People's Hospital of Yibin were analyzed retrospectively. According to the birth weight of the newborn, the subjects were divided into macrosomia group (126 cases) and control group (1 074 cases). Compared the clinical data between the two groups. Logistic regression model was used to analyze the correlation and risk of blood lipid level and the occurrence of fetal macrosomia at late pregnancy. The ROC curve was drawn to evaluate the predictive effect of blood lipid level on the occurrence of macrosomia. Results There was no significant difference in serum TC between the two groups(P>005). The serum TG and LDLC levels in the macrosomia group were higher than those in the control group(P<005). The serum HDLC levels in the macrosomia group were lower than that in the control group (P<005). Logistic regression analysis showed that serum TG and HDLC levels were independent risk factors of macrosomia (P<005). ROC curve analysis showed that serum TG and HDLC levels in women without diabetes mellitus at late pregnancy had predictive value for macrosomia (P<005), the area under the curve was 0878, the sensitivity was 954 %, and the specificity was 684 %. Conclusion The serum TG and HDLC levels in women without diabetes mellitus at late pregnancy are closely related to the occurrence of macrosomia, which has a good predictive value for the occurrence of macrosomia.

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更新日期/Last Update: 2020-04-25